beclobrate

Known as: 2-(4-((4-chlorophenyl)methyl)phenoxy)-2-methylbutanoic acid ethyl ester, Butanoic acid, 2-(4-((4-chlorophenyl)methyl)phenoxy)-2-methyl-, ethyl ester, (+-)- 
A structural analog of clofibrate, converted to its free acid form after oral administration. Beclobrate reduces LDL-cholesterol and increased HDL… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1979-2017
02419792017

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1993
1993
Acyl glucuronides are known to be labile conjugates, which undergo hydrolysis and bind irreversibly to proteins. The lipid… (More)
Is this relevant?
Review
1991
Review
1991
Beclobrat is a new fibric acid derivative with potent cholesterol- and triglyceride-lowering effects. Pharmacodynamic and… (More)
Is this relevant?
1990
1990
Beclobrate, a new fibric acid derivative, displays remarkable lipid lowering activity in rodents. In order to evaluate changes in… (More)
Is this relevant?
1990
1990
The effects of a new fibric acid derivative--beclobrate (Turec, Zyma) on serum lipid and apoprotein concentrations in 63 patients… (More)
Is this relevant?
1990
1990
After three months of beclobrate treatment (100 mg once daily) of 63 patients with primary hyperlipoproteinemia (HLP) significant… (More)
Is this relevant?
1987
1987
The pharmacokinetics of beclobrate (ethyl(+/-)-2-[[alpha-(p-chlorophenyl)-p-tolyl]-oxy]-2-methylbutyrate, SGD 24774), a new lipid… (More)
Is this relevant?
1985
1985
The major pathway of biotransformation of beclobrate [(2-[4-[(4-chlorophenyl)methyl]phenoxy]-2-methylbutyric acid ethyl ester] is… (More)
Is this relevant?
1983
1983
A new diphenylmethane derivative with potent hypolipidemic activity, ethyl-(+/-)-2-[[alpha-(p-chlorophenyl)-p-tolyl]-oxy]-2… (More)
Is this relevant?
1983
1983
Three groups of male Syrian hamsters were fed a lithogenic diet (L), L plus 0.04% ethyl-2-[4-(p-chlorophenyl) methylphenoxy]-2… (More)
Is this relevant?
1983
1983
Two new hypocholesterolemic compounds, ethyl-(+/-)-2-[[alpha-(p-chlorophenyl)-p-tolyl]-oxy]-2-methylbutyrate (Sgd 24 774… (More)
Is this relevant?