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bdellin

National Institutes of Health

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Organic Chemicals

Papers overview

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2019
2019
Purification and characterization of a novel anti-coagulant from the leech Hirudinaria manillensis
Protease inhibitors have been reported rarely from the leech Hirudinaria manillensis. In this study, we purified a novel protease… 
2018
2018
Jalaukavacharan (Indian medicinal leech application) in the management of Raynaud’s disease- A single case Report
In Ayurveda , Sushruta has described the uses of Jalauka (medicinal leech) for the treatment of various medico-surgical disorders… 
2016
2016
Purification and Characterization of a Novel Kazal-Type Trypsin Inhibitor from the Leech of Hirudinaria manillensis
Kazal-type serine proteinase inhibitors are found in a large number of living organisms and play crucial roles in various… 
2004
2004
Protease inhibitors in the alimentary tract of the medicinal leech Hirudo medicinalis: In vivo and in vitro studies
SummaryIn individual leeches the flux of labeled serum through the digestive tract was monitored to measure the rate of digestion… 
2003
2003
A Plasminogen-like Protein Selectively Degrades Stearoyl-CoA Desaturase in Liver Microsomes*
Stearoyl-CoA desaturase (SCD) is an integral membrane protein of the endoplasmic reticulum that is rapidly and selectively… 
2001
2001
Domain and genomic sequence analysis of bdellin-KL, a leech-derived trypsin-plasmin inhibitor.
Bdellin-KL is a trypsin-plasmin inhibitor from Hirudo nipponia, whose N-terminal sequence was identified as a non-classical Kazal… 
1997
1997
Characterization of plasmin-induced platelet aggregation.
This study was undertaken to determine if reocclusion after treatment of myocardial infarction with a tissue-plasminogen… 
Highly Cited
1994
Highly Cited
1994
Platelet-Bound Prekallikrein Promotes Pro-Urokinase-Induced Clot Lysis: A Mechanism for Targeting the Factor XII Dependent Intrinsic Pathway of Fibrinolysis
Summary Clots formed from platelet rich plasma were found to be lysed more readily by low concentrations of pro-urokinase (pro-UK… 
1986
1986
The primary structure of bdellin B-3 from the leech Hirudo medicinalis. Bdellin B-3 is a compact proteinase inhibitor of a "non-classical" Kazal type. It is present in the leech in a high molecular…
A proteinase inhibitor was isolated from extracts of the leech Hirudo medicinalis by gel filtration and anion exchange… 
1971
1971
Trypsin-Plasmin Inhibitors from Leeches Isolation, Amino Acid Composition, Inhibitory Characteristics
Two groups of trypsin-plasmin inhibitors were isolated from commercially available "Hirudin" samples, extracts of the leech… 
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