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bazedoxifene

Known as: 1H-Indol-5-ol, 1-((4-(2-(hexahydro-1H-azepin-1-yl)ethoxy)phenyl)methyl)-2-(4-hydroxyphenyl)-3-methyl-, bazedoxifene/conjugated estrogens 
An indole derivative and third-generation selective estrogen receptor modulator (SERM) with potential antineoplastic activity. Upon administration… 
National Institutes of Health

Related topics

Related topics

9 relations

Broader (3)

Bone Density Conservation AgentsIndolesSelective Estrogen Receptor Modulators

Narrower (3)

DuaveeTSE 424WAY-140424
NCIt Antineoplastic Agent Terminologybazedoxifene / Estrogens, Conjugated (USP)bazedoxifene acetate

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Design, synthesis and biological evaluation of novel indole-xanthendione hybrids as selective estrogen receptor modulators.
2016
2016
Bazedoxifene Ameliorates Homocysteine-Induced Apoptosis and Accumulation of Advanced Glycation End Products by Reducing Oxidative Stress in MC3T3-E1 Cells
Elevated plasma homocysteine (Hcy) level increases the risk of osteoporotic fracture by deteriorating bone quality. However… 
Review
2015
Review
2015
From the Women's Health Initiative to the combination of estrogen and selective estrogen receptor modulators to avoid progestin addition.
Review
2014
Review
2014
Use of FRAX®-based fracture risk assessments to identify patients who will benefit from osteoporosis therapy.
Highly Cited
2013
Highly Cited
2013
Effects of bazedoxifene/conjugated estrogens on endometrial safety and bone in postmenopausal women
ABSTRACT Objectives Bazedoxifene/conjugated estrogens (BZA/CE) has demonstrated efficacy in improving vasomotor and vulvar… 
2012
2012
Relationships Between Changes in Bone Mineral Density or Bone Turnover Markers and Vertebral Fracture Incidence in Patients Treated with Bazedoxifene
We analyzed the relationships between bone mineral density (BMD) or bone turnover marker (BTM) changes and vertebral fracture… 
2011
2011
Effects of bazedoxifene on bone mineral density, bone turnover, and safety in postmenopausal japanese women with osteoporosis
This randomized, double‐blind, placebo‐controlled, dose‐response late phase 2 study evaluated the efficacy and safety of… 
2009
2009
The effects of bazedoxifene on mammographic breast density in postmenopausal women with osteoporosis
Objective: This study aimed to assess quantitative changes in mammographic breast density after 24 months of therapy with… 
2008
2008
Efficacy and safety of bazedoxifene in postmenopausal Asian women
SummaryThis 6-month study examined the efficacy and safety of bazedoxifene 20 mg in postmenopausal Asian women. Bazedoxifene… 
Review
2007
Review
2007
Bazedoxifene and bazedoxifene combined with conjugated estrogens for the management of postmenopausal osteoporosis
Bazedoxifene acetate (WAY-140424; TSE-424) is an investigational non-steroidal indole-based selective estrogen receptor modulator… 
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