bacteriolytic therapy

Therapy that uses anaerobic bacterium, particularly Clostridium novyi-NT, to kill cancer cells within the hypoxic regions of tumors.
National Institutes of Health

Topic mentions per year

Topic mentions per year

2001-2018
01220012018

Papers overview

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Review
2018
Review
2018
Side effects associated with conventional anticancer therapies have prompted the new idea of solid tumor treatment strategy. One… (More)
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2018
2018
Clostridium novyi-NT (CVN-NT) spores germinate in hypoxic regions of tumors and have successfully cured induced neoplasia in… (More)
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Review
2016
Review
2016
This review deals with the role of microorganisms in spontaneous regression of a tumour. Spontaneous cancer regression is a… (More)
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Review
2015
Review
2015
There is an increasing need for new cancer therapies. The antitumour effect of bacterial infection has been well observed and… (More)
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Review
2011
Review
2011
Cancer immunotherapy using bacteria dates back over 150 years. The deeper understanding on how the immune system interferes with… (More)
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Review
2006
Review
2006
The tumour-Clostridium phenomenon describes the specific affinity of spore forming anaerobes to tumour growth. The discovery of… (More)
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2005
2005
The diversity of myxobacteria in a soil niche was explored using culture-dependent and -independent methods. Conventional… (More)
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Review
2003
Review
2003
This review presents diverse approaches to cancer biotherapy including bacteriolytic therapy aimed at inducing apoptosis in tumor… (More)
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Highly Cited
2001
Highly Cited
2001
Current chemotherapeutic approaches for cancer are in part limited by the inability of drugs to destroy neoplastic cells within… (More)
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2001
2001
H and anoxia are pathophysiologic characteristics of most solid tumors (1, 2). For nearly 150 years, nonpathogenic, anaerobic… (More)
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