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bacimethrin

Known as: 4-amino-2-methoxy-5-pyrimidinemethanol 
 
National Institutes of Health

Papers overview

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2017
2017
The canonical kinase (ThiD) that converts the thiamin biosynthesis intermediate hydroxymethylpyrimidine (HMP) monophosphate to… Expand
2017
2017
Paenibacillus thiaminolyticus is the model organism for studying thiaminase I, an enigmatic extracellular enzyme. Originally… Expand
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2016
2016
Bacimethrin (4-amino-5-hydroxymethyl-2-methoxypyrimidine), a natural product isolated from some bacteria, has been implicated as… Expand
2014
2014
Bacimethrin-derived 2′-methoxythiamin pyrophosphate inhibits microbial growth by disrupting metabolic pathways dependent on… Expand
2014
2014
5-Hydroxymethylcytosine (5hmC) is present in T-even phage and mammalian DNA as well as some nucleoside antibiotics, including… Expand
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Highly Cited
2004
Highly Cited
2004
A genetic screen was developed for the identification of genes related to thiamin biosynthesis and degradation. Genes conferring… Expand
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Highly Cited
2001
Highly Cited
2001
The mechanism of bacimethrin (2) toxicity has been determined. This compound is converted to 2'-methoxy-thiamin pyrophosphate (10… Expand
2000
2000
Bacimethrin is an analog of the 4-amino-5-hydroxymethyl-2-methylpyrimidine (HMP) moiety of thiamine and inhibits the growth of… Expand
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