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azosemide

Known as: 2-chloro-5-(1H-tetrazole-5-yl)-N^4-(2-thenyl), azosemid, Benzenesulfonamide, 2-chloro-5-(1H-tetrazol-5-yl)-4-((2-thienylmethyl)amino)- 
A monosulfamyl belonging to the class of loop diuretics. Azosemide inhibits sodium and chloride reabsorption throughout the thick ascending limb of… 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

DiureticsSulfanilamides

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Azosemide is more potent than bumetanide and various other loop diuretics to inhibit the sodium-potassium-chloride-cotransporter human variants hNKCC1A and hNKCC1B
The Na+–K+–2Cl− cotransporter NKCC1 plays a role in neuronal Cl− homeostasis secretion and represents a target for brain… 
Review
2014
Review
2014
Diuretics
Diuretics have been recommended as first-line treatment of hypertension and are also valuable in the management of hypervolemia… 
2009
2009
Beneficial Effects of Torasemide on Systolic Wall Stress and Sympathetic Nervous Activity in Asymptomatic or Mildly Symptomatic Patients With Heart Failure: Comparison With Azosemide
Loop diuretics could adversely influence prognosis due to activation of neurohumoral mechanism in the long term. Previous study… 
Review
2003
Review
2003
Pharmacokinetics and pharmacodynamics of azosemide
Azosemide is used in the treatment of oedematous states and hypertension. The exact mechanism of action is not fully understood… 
2003
2003
Pharmacokinetics and pharmacodynamics of intravenous azosemide in mutant Nagase analbuminemic rats.
This paper reports 1) the increase in expression of CYP1A2 in mutant Nagase analbuminemic rats (NARs), 2) the role of globulin… 
1999
1999
Effects of short-acting and long-acting loop diuretics on heart rate variability in patients with chronic compensated congestive heart failure.
1997
1997
Liver and Gastrointestinal First‐pass Effects of Azosemide in Rats
Since considerable first‐pass effects of azosemide have been reported after oral administration of the drug to rats and man… 
1995
1995
Stability, tissue metabolism, tissue distribution and blood partition of azosemide
Stability of azosemide after incubation in various pH solutions, human plasma, human gastric juice, and rat liver homogenates… 
1984
1984
Teratogenicity of Azosemide, a Loop Diuretic, in Rats, Mice and Rabbits
Teratogenic effects of azosemide, a loop diuretic, were investigated in rats, mice and rabbits. Azosemide was given orally to… 
1978
1978
Clinical and pharmacological investigations of the new saluretic azosemid
SummaryPle 1053 (Azosemid) is a diuretic which resembles furosemide chemically and in its mode of action. When administered… 
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