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aziridine-2,3-dicarboxylate

 
National Institutes of Health

Papers overview

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Review
2019
Review
2019
&NA; Leishmaniasis is considered a serious public health problem and the current available therapy has several disadvantages… Expand
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2018
2018
In the present work a series of aziridine-2,3-dicarboxylate inhibitors of papain-like cysteine proteases was designed… Expand
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2015
2015
ABSTRACT Leishmaniasis is one of the major neglected tropical diseases of the world. Druggable targets are the parasite cysteine… Expand
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2009
2009
Quantum chemical computations on appropriate model systems are used for a rational design of aziridine-based inhibitors of… Expand
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Highly Cited
2006
Highly Cited
2006
The protozoan parasite Trypanosoma brucei causes Human African trypanosomiasis, which is fatal if left untreated. Due to the… Expand
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2006
2006
A comprehensive screening of N‐acylated aziridine (aziridide) based cysteine protease inhibitors containing either Boc‐Leu‐Caa… Expand
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2004
2004
Abstract Cysteine proteases have been implicated in a variety of processes essential for the survival and progression of the… Expand
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2000
2000
Peptides containing aziridine-2,3-dicarboxylate (Azi) as electrophilic building block are evaluated as inhibitors of the cysteine… Expand
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