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axis specification

Known as: axis determination 
The establishment, maintenance and elaboration of a pattern along a line or around a point. [GOC:dph, GOC:go_curators, GOC:isa_complete]
National Institutes of Health

Papers overview

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Highly Cited
2005
Highly Cited
2005
Axin1 and its homolog Axin2/conductin/Axil are negative regulators of the canonical Wnt pathway that suppress signal transduction… Expand
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Highly Cited
2003
Highly Cited
2003
The vertebrate body plan has conserved handed left-right (LR) asymmetry that is manifested in the heart, lungs, and gut. Leftward… Expand
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Highly Cited
2003
Highly Cited
2003
The PAR-4 and PAR-1 kinases are necessary for the formation of the anterior–posterior (A–P) axis in Caenorhabditis elegans. PAR-1… Expand
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Highly Cited
2000
Highly Cited
2000
Holoprosencephaly (HPE) is the most common structural defect of the developing forebrain in humans (1 in 250 conceptuses, 1 in 16… Expand
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Review
1998
Review
1998
After fertilization of Xenopus eggs, the cortex rotates relative to the cytoplasm, resulting in the formation of a cytoplasmic… Expand
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Highly Cited
1998
Highly Cited
1998
Signaling by the Wnt family of extracellular proteins is critical in a variety of developmental processes in which cell and… Expand
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Highly Cited
1997
Highly Cited
1997
Genetic experiments suggest that polarization of the oocyte is linked directly to the initial cell fate determination that… Expand
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Highly Cited
1995
Highly Cited
1995
One of the first intercellular signalling events in the vertebrate embryo leads to mesoderm formation and axis determination. In… Expand
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Highly Cited
1994
Highly Cited
1994
The cadherin-catenin complex has an important role in cell-cell adhesion and may also function in signaling pathways. We report… Expand
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Highly Cited
1993
Highly Cited
1993
The wingless (wg) and decapentaplegic (dpp) genes of Drosophila encode homologs of secreted growth factors and are required for… Expand
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