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aureobasidin A

Known as: BASIFUNGIN, cyclo-(D-Hmp(1)-L-MeVal(2)-L-Phe(3)-L-MePhe(4)-L-Pro(5)-L-aIle+ ++(6)-L-MeVal(7)-L-Leu(8)-L-betaHOMeVal(9)) 
An orally available cyclic depsipeptide antibiotic produced by Aureobasidium pullulans that is a fungicide at low concentrations. Aureobasidin A… 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (3)

Antifungal AgentsDepsipeptidesEnzyme Inhibitors

Narrower (1)

LY 295337

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Ceramide signals for initiation of yeast mating-specific cell cycle arrest
ABSTRACT Sphingolipids are major constituents of membranes. A number of S. cerevisiae sphingolipid intermediates such as long… 
2014
2014
Characterization of yeast mutants lacking alkaline ceramidases YPC1 and YDC1.
Humans and yeast possess alkaline ceramidases located in the early secretory pathway. Single deletions of the highly homologous… 
2013
2013
The inhibitory effects of aureobasidin A on Candida planktonic and biofilm cells
Aureobasidin A (AbA) is a cyclic depsipeptide antifungal compound that inhibits a wide range of pathogenic fungi. In this study… 
2009
2009
Contribution to the synthesis of aureobasidin A. Synthesis of cyclopeptolides containing the sequence leucyl-N-methyl-beta-hydroxyvalyl-(2R)-oxy-(3R)-methyl-pentanoi c acid.
The efficient antimycotic agent aureobasidin A, isolated from the culture broth of Aureobasidium pullulans R 106, and the [(R… 
2008
2008
Development of predictive in silico model for cyclosporine- and aureobasidin-based P-glycoprotein inhibitors employing receptor surface analysis.
2007
2007
Inhibition of Leishmania (Leishmania) amazonensis growth and infectivity by aureobasidin A.
OBJECTIVES To study the effect of aureobasidin A, an inhibitor of inositol phosphorylceramide (IPC) synthase, on Leishmania… 
Review
2004
Review
2004
IPC synthase as a useful target for antifungal drugs.
Inositol phosphorylceramide (IPC) synthase is a common and essential enzyme in fungi and plants, which catalyzes the transfer of… 
1999
1999
Unique molecular conformation of aureobasidin A, a highly amide N-methylated cyclic depsipeptide with potent antifungal activity: X-ray crystal structure and molecular modeling studies.
A structural feature of aureobasidins, cyclic depsipeptide antibiotics produced by Aureobasidium pullulans R106, is the N… 
1998
1998
Syntheses of antifungal aureobasidin A analogs with alkyl chains for structure-activity relationship.
The syntheses of aureobasidin A (AbA) derivatives with alkyl chains and their in vitro structure-biological activity… 
1998
1998
Aureobasidins as new inhibitors of P-glycoprotein in multidrug resistant tumor cells.
Cyclic depsipeptide antibiotic aureobasidin A (AbA) and its analogs were tested for the inhibitory activity of P-glycoprotein in… 
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