Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

attachment of spindle microtubules to kinetochore

Known as: spindle kinetochore attachment, attachment of spindle microtubules to chromosome, microtubule anchoring at kinetochore 
The process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex. [GOC:vw, PMID:10322137]
National Institutes of Health

Related topics

Related topics

4 relations

Narrower (2)

attachment of spindle microtubules to kinetochore involved in homologous chromosome segregationmicrotubule binding
kinetochore-microtubule interaction

Broader (1)

nuclear chromosome segregation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Kinetochore–microtubule attachment is sufficient to satisfy the human spindle assembly checkpoint
The spindle assembly checkpoint (SAC) is a genome surveillance mechanism that protects against aneuploidization. Despite profound… Expand
  • figure 2
  • figure 3
Is this relevant?
Highly Cited
2015
Highly Cited
2015
A molecular basis for the differential roles of Bub1 and BubR1 in the spindle assembly checkpoint
The spindle assembly checkpoint (SAC) monitors and promotes kinetochore-microtubule attachment during mitosis. Bub1 and BubR1… Expand
Is this relevant?
Highly Cited
2012
Highly Cited
2012
The Ndc80 kinetochore complex directly modulates microtubule dynamics.
The conserved Ndc80 complex is an essential microtubule-binding component of the kinetochore. Recent findings suggest that the… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2011
Highly Cited
2011
Temporal changes in Hec1 phosphorylation control kinetochore-microtubule attachment stability during mitosis.
Precise control of the attachment strength between kinetochores and spindle microtubules is essential to preserve genomic… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2011
2011
CENP-U cooperates with Hec1 to orchestrate kinetochore-microtubule attachment.
Mitosis is an orchestration of dynamic interaction between chromosomes and spindle microtubules by which genomic materials are… Expand
Is this relevant?
2010
2010
MST1 Limits the Kinase Activity of Aurora B to Promote Stable Kinetochore-Microtubule Attachment
The establishment and maintenance of proper attachment of kinetochores to microtubules are required to prevent chromosome… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2009
Highly Cited
2009
RAMA1 is a novel kinetochore protein involved in kinetochore-microtubule attachment.
During mitosis, kinetochores need to attach to microtubules emanating from spindle poles. Several protein complexes have been… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2009
Highly Cited
2009
Ipl1-dependent phosphorylation of Dam1 is reduced by tension applied on kinetochores.
The conserved Aurora B protein kinase (Ipl1 in Saccharomyces cerevisiae) is essential for ensuring that sister kinetochores… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2008
Highly Cited
2008
Histone deacetylase 3 localizes to the mitotic spindle and is required for kinetochore-microtubule attachment.
Protein acetylation and deacetylation play key roles in multiple physiological functions. Histone deacetylase 3 (HDAC3) is a… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2004
Highly Cited
2004
Survivin dynamics increases at centromeres during G2/M phase transition and is regulated by microtubule-attachment and Aurora B kinase activity.
The inhibitor of apoptosis protein survivin is implicated in two key biological events: in the control of cell proliferation and… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • table 1
Is this relevant?
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License
ACCEPT & CONTINUE