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astrocyte differentiation

The process in which a relatively unspecialized cell acquires the specialized features of an astrocyte. An astrocyte is the most abundant type of… 
National Institutes of Health

Related topics

Related topics

5 relations

Narrower (2)

astrocyte developmentastrocyte fate commitment

Broader (1)

central nervous system development
glial cell differentiationnegative regulation of astrocyte differentiation

Papers overview

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Highly Cited
2011
Highly Cited
2011
Astrocytes from the Contused Spinal Cord Inhibit Oligodendrocyte Differentiation of Adult Oligodendrocyte Precursor Cells by Increasing the Expression of Bone Morphogenetic Proteins
Promotion of remyelination is an important therapeutic strategy to facilitate functional recovery after traumatic spinal cord… 
Review
2007
Review
2007
Cell fate specification in the mammalian telencephalon
Highly Cited
2007
Highly Cited
2007
A crucial role for Olig2 in white matter astrocyte development
The mechanisms underlying astrocyte heterogeneity in the developing mouse brain are poorly understood. The bHLH transcription… 
Highly Cited
2004
Highly Cited
2004
Molecular diversity of astrocytes with implications for neurological disorders.
The astrocyte represents the most abundant yet least understood cell type of the CNS. Here, we use a stringent experimental… 
Highly Cited
2001
Highly Cited
2001
Induction of Astrocyte Differentiation by Endothelial Cells
Here we have investigated the mechanisms that control astrocyte differentiation within the developing rat optic nerve. Astrocytes… 
Highly Cited
1994
Highly Cited
1994
Ciliary neurotrophic factor and leukemia inhibitory factor promote the generation, maturation and survival of oligodendrocytes in vitro.
We have found that CNTF and LIF are pleiotropic modulators of development in the O-2A lineage. Both molecules enhanced the… 
Highly Cited
1990
Highly Cited
1990
Extracellular matrix-associated molecules collaborate with ciliary neurotrophic factor to induce type-2 astrocyte development
O-2A progenitor cells give rise to both oligodendrocytes and type-2 astrocytes in vitro. Whereas oligodendrocyte differentiation… 
Highly Cited
1988
Highly Cited
1988
Ciliary neurotrophic factor induces type-2 astrocyte differentiation in culture
We have been studying a population of bipotential glial progenitor cells in the perinatal rat optic nerve and brain in an attempt… 
Highly Cited
1988
Highly Cited
1988
Type-2 astrocyte development in rat brain cultures is initiated by a CNTF like protein produced by type-1 astrocytes
Highly Cited
1984
Highly Cited
1984
The in vitro differentiation of a bipotential glial progenitor cell.
We have studied the properties of a glial progenitor cell from 7‐day‐old rat optic nerve that differentiates in vitro into an… 
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