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asfotase alfa

Known as: Asfotase alpha 
 
National Institutes of Health

Papers overview

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2019
2019
Hypophosphatasia (HPP) features low tissue-nonspecific alkaline phosphatase (TNSALP) isoenzyme activity resulting in… Expand
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2019
2019
BACKGROUND Our previous phase 2, open-label study of 11 infants and young children with life-threatening perinatal or infantile… Expand
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2019
2019
Abstract Context Long-term data on enzyme replacement treatment of hypophosphatasia (HPP) are limited. Objective To evaluate… Expand
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2018
2018
ABSTRACT Infants and children with hypophosphatasia (HPP) treated with asfotase alfa show improvement in bone mineralization and… Expand
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2017
2017
OBJECTIVE Hypophosphatasia (HPP) is a rare skeletal disease characterized by hypomineralization and low alkaline phosphatase… Expand
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2017
2017
Hypophosphatasia is an inherited disease characterized by reduced alkaline phosphatase activity, extracellular accumulation of… Expand
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Highly Cited
2016
Highly Cited
2016
CONTEXT Hypophosphatasia (HPP) is an inborn error of metabolism that, in its most severe perinatal and infantile forms, results… Expand
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Highly Cited
2016
Highly Cited
2016
Background. Hypophosphatasia (HPP) is caused by loss-of-function mutation(s) of the gene that encodes the tissue-nonspecific… Expand
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Review
2016
Review
2016
  • Hideo Orimo
  • Therapeutics and clinical risk management
  • 2016
  • Corpus ID: 16286522
Hypophosphatasia (HPP) is an inherited systemic bone disease that is characterized by bone hypomineralization. HPP is classified… Expand
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Review
2016
Review
2016
Hypophosphatasia (HPP) is a rare disease caused by loss-of-function mutations in the tissue-nonspecific alkaline phosphatase… Expand
Is this relevant?