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ascofuranone

National Institutes of Health

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Sesquiterpenes

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2010
2010
Trypanosome alternative oxidase, a potential therapeutic target for sleeping sickness, is conserved among Trypanosoma brucei subspecies.
2009
2009
Suppression of PAI‐1 expression through inhibition of the EGFR‐mediated signaling cascade in rat kidney fibroblast by ascofuranone
Fibrosis in glomerulosclerosis causes progressive loss of renal function. Transforming growth factor (TGF)‐β, one of the major… 
2009
2009
Comparative proteome analysis of TGF‐β1‐induced fibrosis processes in normal rat kidney interstitial fibroblast cells in response to ascofuranone
Transforming growth factor‐β1 (TGF‐β1) has a wide range of biological functions such as the regulation of cell growth… 
1987
1987
Macrophage-specific effect on lipid metabolism by an antibiotic, ascofuranone.
Ascofuranone (AF) enhanced glucose consumption of splenocytes and macrophages, while it enhanced incorporation of [14C]acetate… 
1986
1986
In vitro effects of an antitumor antibiotic, ascofuranone, on the murine immune system.
Effects of an antitumor antibiotic, ascofuranone (AF) on the murine immune system were studied. Unlike lectins, AF did not induce… 
1986
1986
Activation of natural cytotoxic activity and concomitant reduction of triglyceride content of murine spleen, treated with an antitumor antibiotic, ascofuranone.
Ascofuranone (AF) elevated natural cytotoxic activity of spleen when it was administered intraperitoneally to male mice. The… 
1983
1983
Effects of an antitumor agent, ascofuranone, on the macromolecular syntheses of intact cells.
Ascofuranone (AF) has antitumor protective property on experimental tumors. We examined the action of AF on lymphoma L5178Y to… 
1981
1981
Unusual concentration of urine and prevention of polydipsia by fungal prenylphenols in DOCA hypertensive rats.
1975
1975
Effect of ascofuranone on serum lipids of rats fed a cholesterol rich diet.
Ascofuranone, a fungal metabolite, significantly reduced serum lipid levels, when orally administered to male Wistar rats fed a… 
1973
1973
Hypolipidemic property of ascofuranone.
Ascofuranone significantly reduced serum lipid levels of rats fed with normal diet 6 hours after a single oral administration of… 
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