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artelinic acid

Known as: sodium artelinate 
National Institutes of Health

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Artemisinins

Papers overview

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2011
2011
Artesunate and artelinic acid: association of embryotoxicity, reticulocytopenia, and delayed stimulation of hematopoiesis in pregnant rats.
The artemisinin antimalarials cause embryo death and malformations in animals by killing embryonic erythroblasts. Groups of… 
2007
2007
Neurotoxicity and Toxicokinetics of Artelinic Acid Following Repeated Oral Administration in Rats
Neurotoxicity secondary to oil-soluble artemisinins has been reported in various animal species. The onset of neurotoxicity and… 
2004
2004
Development of a reversed-phase thin-layer chromatographic method for artemisinin and its derivatives.
In this study a clear separation between seven analogues of artemisinin on thin-layer chromatography (TLC) is presented. The… 
2003
2003
Transmission-blocking activity of tafenoquine (WR-238605) and artelinic acid against naturally circulating strains of Plasmodium vivax in Thailand.
The sporontocidal activity of tafenoquine (WR-238605) and artelinic acid was determined against naturally circulating isolates of… 
2002
2002
Orally active, water-soluble antimalarial 3-aryltrioxanes: short synthesis and preclinical efficacy testing in rodents.
Short chemical syntheses of four new antimalarial trioxanes are presented, starting with inexpensive and commercially available… 
1997
1997
Antimalarial activity of new dihydroartemisinin derivatives. 7. 4-(p-substituted phenyl)-4(R or S)-[10(alpha or beta)-dihydroartemisininoxy]butyric acids.
To search for water soluble dihydroartemisinin derivatives with higher efficacy and longer plasma half-life than artesunic or… 
Highly Cited
1995
Highly Cited
1995
Antimalarial activity of new dihydroartemisinin derivatives. 6. alpha-Alkylbenzylic ethers.
A series of diastereomeric dihydroartemisinin alpha-alkylbenzylic ethers was synthesized in search for analogs with higher… 
1992
1992
Hepatic metabolism of artemisinin drugs--III. Induction of hydrogen peroxide production in rat liver microsomes by artemisinin drugs.
1991
1991
Transdermal artelinic acid: an effective treatment for Plasmodium berghei-infected mice.
Artelinic acid, a derivative of the naturally occurring antimalarial artemisinin, has been incorporated into a gel suitable for… 
1990
1990
Plasmodium berghei: the antimalarial action of artemisinin and sodium artelinate in vivo and in vitro, studied by flow cytometry.
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