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artelinic acid
Known as:
sodium artelinate
National Institutes of Health
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1 relation
Broader (1)
Artemisinins
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2007
2007
Neurotoxicity and Toxicokinetics of Artelinic Acid Following Repeated Oral Administration in Rats
Y. Si
,
Qigui Li
,
+4 authors
T. Johnson
International journal of toxicology
2007
Corpus ID: 5672864
Neurotoxicity secondary to oil-soluble artemisinins has been reported in various animal species. The onset of neurotoxicity and…
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2004
2004
Development of a reversed-phase thin-layer chromatographic method for artemisinin and its derivatives.
M. Gabriëls
,
J. Plaizier-Vercammen
Journal of Chromatographic Science
2004
Corpus ID: 34362047
In this study a clear separation between seven analogues of artemisinin on thin-layer chromatography (TLC) is presented. The…
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2002
2002
Orally active, water-soluble antimalarial 3-aryltrioxanes: short synthesis and preclinical efficacy testing in rodents.
G. Posner
,
H. Jeon
,
+4 authors
T. Shapiro
Journal of Medicinal Chemistry
2002
Corpus ID: 11167725
Short chemical syntheses of four new antimalarial trioxanes are presented, starting with inexpensive and commercially available…
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1997
1997
Antimalarial activity of new dihydroartemisinin derivatives. 7. 4-(p-substituted phenyl)-4(R or S)-[10(alpha or beta)-dihydroartemisininoxy]butyric acids.
A. Lin
,
A. B. Zikry
,
D. Kyle
Journal of Medicinal Chemistry
1997
Corpus ID: 37095447
To search for water soluble dihydroartemisinin derivatives with higher efficacy and longer plasma half-life than artesunic or…
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1997
1997
Biomimetic Metabolism of Artelinic Acid by Chemical Cytochrome P-450 Model Systems
O. R. Idowu
,
A. Lin
,
J. Grace
,
J. Peggins
Pharmaceutical Research
1997
Corpus ID: 29288560
AbstractPurpose. To study the reaction of artelinic acid with chemical model systems of cytochrome P-450 as a means of obtaining…
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Highly Cited
1995
Highly Cited
1995
Antimalarial activity of new dihydroartemisinin derivatives. 6. alpha-Alkylbenzylic ethers.
A. Lin
,
Robert E. Miller
Journal of Medicinal Chemistry
1995
Corpus ID: 23996297
A series of diastereomeric dihydroartemisinin alpha-alkylbenzylic ethers was synthesized in search for analogs with higher…
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1994
1994
Antimalarial activity of dihydroartemisinin derivatives by transdermal application.
A. Lin
,
A. Ager
,
D. Klayman
American Journal of Tropical Medicine and Hygiene
1994
Corpus ID: 22361491
In addition to artelinic acid, which was demonstrated previously to possess good prophylactic as well as curative antimalarial…
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1992
1992
Hepatic metabolism of artemisinin drugs--III. Induction of hydrogen peroxide production in rat liver microsomes by artemisinin drugs.
V. Leskovac
,
J. Peggins
Comparative biochemistry and physiology. C…
1992
Corpus ID: 22733118
1991
1991
Transdermal artelinic acid: an effective treatment for Plasmodium berghei-infected mice.
D. Klayman
,
A. Ager
,
L. Fleckenstein
,
A. Lin
American Journal of Tropical Medicine and Hygiene
1991
Corpus ID: 31974672
Artelinic acid, a derivative of the naturally occurring antimalarial artemisinin, has been incorporated into a gel suitable for…
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1990
1990
Plasmodium berghei: the antimalarial action of artemisinin and sodium artelinate in vivo and in vitro, studied by flow cytometry.
P. H. Vianen
,
D. Klayman
,
+4 authors
B. Mons
Experimental parasitology
1990
Corpus ID: 37968896
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