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argadin

Known as: cyclo(N(omega)-acetyl-L-arginyl-D-prolyl-homoseryl-histidyl-L- 2-aminoadipyl) 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2000-2016
01220002016

Related topics

Related topics

1 relation

Broader (1)

Cyclic Peptides

Related mentions per year

Related mentions per year

1955-2018
1960198020002020
argadin
Cyclic Peptides

Papers overview

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2016
2016
Molecular Orbital Study of the Formation of Intramolecular Hydrogen Bonding of a Ligand Molecule in a Protein Aromatic Hydrophobic Pocket.
The natural product argadin is a cyclopentapeptide chitinase inhibitor that binds to chitinase B (ChiB) from the pathogenic… (More)
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2011
2011
Functional comparison of recombinant acidic mammalian chitinase with enzyme from murine bronchoalveolar lavage.
Acidic mammalian chitinase (AMCase) is an enzyme that selectively degrades the biopolymer chitin. Several chitinase enzymes are… (More)
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Review
2009
Review
2009
Chitinase Inhibitors and Chitin Mimetics for Crop Protection
Pathogen and pest management is a key element in agriculture. The Integrated Pest Management concept relies on the availability… (More)
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2008
2008
Computational analysis of the binding affinities of the natural-product cyclopentapeptides argifin and argadin to chitinase B from Serratia marcescens.
Molecular dynamics (MD) simulations and the molecular mechanics Poisson-Boltzmann surface area (MM-PBSA) method were applied to… (More)
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2006
2006
First Synthesis of Argadin: A Nanomolar Inhibitor of Family-18 Chitinases
The first synthesis of the cyclic peptide natural product, argadin is reported. Use of a solid-phase approach featuring sidechain… (More)
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2006
2006
Screening-based Discovery and Structural Dissection
Family 18 chitinases play key roles in the life cycles of a variety of organisms ranging from bacteria to man. Very recently it… (More)
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2005
2005
Specificity and affinity of natural product cyclopentapeptide inhibitors against A. fumigatus, human, and bacterial chitinases.
Family 18 chitinases play key roles in organisms ranging from bacteria to man. There is a need for specific, potent inhibitors to… (More)
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2004
2004
Structure-based exploration of cyclic dipeptide chitinase inhibitors.
Family 18 chitinases play an essential role in a range of pathogens and pests. Several inhibitors are known, including the potent… (More)
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2002
2002
High-resolution structures of a chitinase complexed with natural product cyclopentapeptide inhibitors: mimicry of carbohydrate substrate.
Over the past years, family 18 chitinases have been validated as potential targets for the design of drugs against human… (More)
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2000
2000
Argadin, a new chitinase inhibitor, produced by Clonostachys sp. FO-7314.
A new chitinase inhibitor, designated as argadin (1), was isolated from the cultured broth of a fungal strain FO-7314. The strain… (More)
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