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arachidonate 15-lipoxygenase activity
Known as:
arachidonate omega6 lipoxygenase activity
, arachidonate omega(6) lipoxygenase activity
, linoleic acid omega6-lipoxygenase activity
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Catalysis of the reaction: arachidonate + O2 = (5Z,8Z,11Z,13E)-(15S)-15-hydroperoxyicosa-5,8,11,13-tetraenoate. [EC:1.13.11.33]
National Institutes of Health
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Highly Cited
2013
Highly Cited
2013
endothelial cells and platelet activation Estrogen stimulates arachidonoylethanolamide release from human
M. Maccarrone
,
M. Bari
,
N. Battista
,
A. Finazzi-Agrò
2013
Corpus ID: 22559309
http://bloodjournal.hematologylibrary.org/content/100/12/4040.full.html Updated information and services can be found at: (2497…
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Highly Cited
2005
Highly Cited
2005
In chronic fatigue syndrome, the decreased levels of omega-3 poly-unsaturated fatty acids are related to lowered serum zinc and defects in T cell activation.
M. Maes
,
I. Mihaylova
,
J. Leunis
Neuro - endocrinology letters
2005
Corpus ID: 24932041
There is now evidence that major depression is accompanied by decreased levels of omega3 poly-unsaturated fatty acids (PUFA…
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1999
1999
Interleukin-4 enhances 15-lipoxygenase activity and incorporation of 15(S)-HETE into cellular phospholipids in cultured pulmonary epithelial cells.
M. Profita
,
A. Vignola
,
+5 authors
G. Bonsignore
American Journal of Respiratory Cell and…
1999
Corpus ID: 29950162
15(S)-Hydroxyeicosatetraenoic acid (15[S]-HETE) is a 15-lipoxygenase (15-LO) metabolite that may play an important role in…
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Highly Cited
1996
Highly Cited
1996
Activation of NADPH oxidase required for macrophage-mediated oxidation of low-density lipoprotein.
M. Aviram
,
M. Rosenblat
,
Amos Etzioni
,
R. Levy
Metabolism: Clinical and Experimental
1996
Corpus ID: 34521900
1993
1993
Arachidonic acid 15-lipoxygenase and traces of E prostaglandins in purified human prostasomes.
E. Oliw
,
R. Fabiani
,
L. Johansson
,
G. Ronquist
Journal of Reproduction and Fertility
1993
Corpus ID: 30433060
Human spermatozoa are associated with arachidonate 15-lipoxygenase activity. This activity could be due to 15-lipoxygenase in…
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Highly Cited
1992
Highly Cited
1992
Cellular oxidative modification of low density lipoprotein does not require lipoxygenases.
C. Sparrow
,
Joanne Olszewski
Proceedings of the National Academy of Sciences…
1992
Corpus ID: 7641957
The oxidative modification of low density lipoprotein (LDL) may play an important role in the pathogenesis of atherosclerosis…
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1991
1991
Purification of two forms of arachidonate 15-lipoxygenase from human leukocytes.
T. Izumi
,
O. Rådmark
,
H. Jörnvall
,
B. Samuelsson
European Journal of Biochemistry
1991
Corpus ID: 21482012
Two different proteins with arachidonate 15-lipoxygenase activity have been purified to near homogeneity from human leukocytes…
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Highly Cited
1990
Highly Cited
1990
Expression of cloned human reticulocyte 15-lipoxygenase and immunological evidence that 15-lipoxygenases of different cell types are related.
Elliott Sigal
,
D. Grunberger
,
Ella Highland
,
C. Gross
,
R. A. Dixon
,
Charles S. Craik
Journal of Biological Chemistry
1990
Corpus ID: 45273693
Highly Cited
1987
Highly Cited
1987
Vascular lipoxygenase activity: synthesis of 15-hydroxyeicosatetraenoic acid from arachidonic acid by blood vessels and cultured vascular endothelial cells.
H. Takayama
,
M. Gimbrone
,
A. Schafer
Thrombosis Research
1987
Corpus ID: 24000405
1985
1985
Cell damage unmasks 15-lipoxygenase activity in human neutrophils.
J. McGuire
,
J. McGee
,
N. Crittenden
,
F. Fitzpatrick
Journal of Biological Chemistry
1985
Corpus ID: 19521784
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