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apogossypolone

Known as: ApoG2 cpd 
National Institutes of Health

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Broader (1)

Gossypol
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Nanosystem Integrated with Photosensitizer and Novel Targeting Chemotherapy Agent for Gastric Cancer Chemo-Photodynamic Combined Therapy.
The poor cell membrane penetration ability of photosensitizers resulted in the limited antitumor effect, thereby hampered their… 
2018
2018
Apogossypolone inhibits the proliferation of LNCaP cells in vitro and in vivo
An interested reader drew to the attention of the Editorial Board of Molecular Medicine Reports that certain data in the above… 
2017
2017
Apogossypolone induces apoptosis and autophagy in nasopharyngeal carcinoma cells in an in vitro and in vivo study
Nasopharyngeal carcinoma (NPC) has a high incidence and mortality rate, particularly in Southern China. Apogossypolone (ApoG2) is… 
2015
2015
ApoG2 inhibits the antiapoptotic protein, Mcl‑1, and induces mitochondria‑dependent apoptosis in human colorectal cancer cells.
Colorectal cancer (CRC) is a worldwide malignancy of high incidence and mortality. At present, there is a lack of effective drugs… 
2014
2014
Growth inhibitory effects of gossypol and related compounds on fungal cotton root pathogens
The effect of the terpenoids gossypol, 6‐methoxygossypol, 6,6′‐dimethoxygossypol, gossypolone and apogossypolone on growth of… 
2011
2011
Apogossypolone targets mitochondria and light enhances its anticancer activity by stimulating generation of singlet oxygen and reactive oxygen species
Apogossypolone (ApoG2), a novel derivative of gossypol, has been shown to be a potent inhibitor of antiapoptotic Bcl-2 family… 
2010
2010
Apogossypolone, a novel inhibitor of antiapoptotic Bcl-2 family proteins, induces autophagy of PC-3 and LNCaP prostate cancer cells in vitro.
Limited treatment options are available for aggressive prostate cancer. Gossypol has been reported to have a potent anticancer… 
2009
2009
Design and Synthesis of a Gossypol Derivative with Improved Antitumor Activities
A novel chemical process has been devised for the synthesis of a new derivative of gossypol, 6,7,6′,7′‐tetrahydroxy‐5,5… 
2008
2008
ApoG2 inhibits antiapoptotic Bcl-2 family proteins and induces mitochondria-dependent apoptosis in human lymphoma U937 cells
Lymphoma is one of the most common types of hematological malignancies and proteins from the Bcl-2 family are highly expressed in… 
2008
2008
ApoG 2 inhibits antiapoptotic Bcl-2 family proteins and induces mitochondria-dependent apoptosis in human lymphoma U 937 cells
Lymphoma is one of the most common types of hematological malignancies and proteins from the Bcl-2 family are highly expressed in… 
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