Gossypol

Known as: (+/-)-Gossypol, Gossypol [Chemical/Ingredient], 2,2'-bis[1,6,7-Trihydroxy-4-methyl-5-isopropyl-8-aldehydonaphthalene 
An orally-active polyphenolic aldehyde with potential antineoplastic activity. Derived primarily from unrefined cottonseed oil, gossypol induces cell… (More)
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
We have sequenced and assembled a draft genome of G. raimondii, whose progenitor is the putative contributor of the D subgenome… (More)
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Highly Cited
2007
Highly Cited
2007
We identify a cytochrome P450 gene (CYP6AE14) from cotton bollworm (Helicoverpa armigera), which permits this herbivore to… (More)
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Highly Cited
2006
Highly Cited
2006
Global cottonseed production can potentially provide the protein requirements for half a billion people per year; however, it is… (More)
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Highly Cited
2005
Highly Cited
2005
Aberrant overexpression of antiapoptotic members of the Bcl-2 protein family, including Bcl-2 and Bcl-X(L), contributes to… (More)
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Highly Cited
2003
Highly Cited
2003
Gossypol, a male contraceptive drug, has been demonstrated to have antiproliferative and antimetastatic effects on many kinds of… (More)
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Highly Cited
2002
Highly Cited
2002
Plant antimicrobials are not used as systemic antibiotics at present. The main reason for this is their low level of activity… (More)
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Highly Cited
2001
Highly Cited
2001
Gossypol has demonstrated in vitro effects on cell cycle regulation and anti-tumor activity against mammary carcinoma cell lines… (More)
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1999
1999
Gossypol, a polyphenolic compound which depletes cellular energy by inhibition of several intracellular dehydrogenases, has been… (More)
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Highly Cited
1993
Highly Cited
1993
Medical treatment of metastatic adrenal cancer is largely unsuccessful and has considerable toxicity. We previously demonstrated… (More)
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1992
1992
A total of 34 patients with advanced cancer were given weekly or daily escalating doses of oral gossypol, a cottonseed-oil… (More)
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