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Gossypol

Known as: (+/-)-Gossypol, Gossypol [Chemical/Ingredient], 2,2'-bis[1,6,7-Trihydroxy-4-methyl-5-isopropyl-8-aldehydonaphthalene 
An orally-active polyphenolic aldehyde with potential antineoplastic activity. Derived primarily from unrefined cottonseed oil, gossypol induces cell… Expand
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
We have sequenced and assembled a draft genome of G. raimondii, whose progenitor is the putative contributor of the D subgenome… Expand
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Highly Cited
2008
Highly Cited
2008
Gossypol, a cottonseed extract derivative, acts as a BH3-mimetic, binding to the BH3 pocket of antiapoptotic proteins and… Expand
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Highly Cited
2007
Highly Cited
2007
We identify a cytochrome P450 gene (CYP6AE14) from cotton bollworm (Helicoverpa armigera), which permits this herbivore to… Expand
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Highly Cited
2006
Highly Cited
2006
Global cottonseed production can potentially provide the protein requirements for half a billion people per year; however, it is… Expand
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Highly Cited
2006
Highly Cited
2006
Gossypol is a sesquiterpene that occurs naturally in seed and other parts of the cotton plant. Because of restricted rotation… Expand
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Highly Cited
2004
Highly Cited
2004
Gossypol has demonstrated in vitro effects on cell cycle regulation and anti-tumor activity against mammary carcinoma cell lines… Expand
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Highly Cited
2004
Highly Cited
2004
Gossypol, a polyphenolic compound which depletes cellular energy by inhibition of several intracellular dehydrogenases, has been… Expand
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Review
2002
Review
2002
Gossypol is a polyphenol isolated from the seed, roots, and stem of the cotton plant (Gossypium sp.). The substance, a yellow… Expand
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Highly Cited
1993
Highly Cited
1993
Medical treatment of metastatic adrenal cancer is largely unsuccessful and has considerable toxicity. We previously demonstrated… Expand
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Highly Cited
1989
Highly Cited
1989
The plant-derived phenolic compounds gossypol, quercetin and myricetin are powerful inhibitors of iron-induced lipid peroxidation… Expand
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