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aplidine

Known as: N-[1-(1,2-Dioxopropyl)-L-prolyl]didemnin A, DDB, APLD 
A cyclic depsipeptide isolated from the marine tunicate Aplidium albicans. Plitidepsin displays a broad spectrum of antitumor activities, inducing… Expand
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
OBJECTIVE To develop evidence-based clinical practice guidelines for interventional techniques in the diagnosis and treatment of… Expand
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Highly Cited
2011
Highly Cited
2011
Weight loss can have substantial health benefits for overweight or obese persons; however, the ratio of fat:lean tissue loss may… Expand
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Review
2009
Review
2009
BACKGROUND Comprehensive, evidence-based guidelines for interventional techniques in the management of chronic spinal pain are… Expand
Highly Cited
2009
Highly Cited
2009
2 Abstract: Extracts of marine algae, sponge and humic acid sediments were tested against different bacterial pathogens by well… Expand
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Highly Cited
2007
Highly Cited
2007
IntroductionMicrovascular alterations may play an important role in the development of organ failure in critically ill patients… Expand
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Highly Cited
2005
Highly Cited
2005
The xeroderma pigmentosum group C (XPC) protein complex plays a key role in recognizing DNA damage throughout the genome for… Expand
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Highly Cited
2002
Highly Cited
2002
Objective: The objective of this study was to assess the feasibility, safety, and outcome of laparoscopic liver resection for… Expand
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Review
2001
Review
2001
Many pharmaceutical agents have been discovered by screening natural products from plants, animals, marine organisms and… Expand
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Highly Cited
2001
Highly Cited
2001
DDB has been implicated in DNA repair as well as transcription. Mutations in DDB have been correlated with the repair-deficiency… Expand
Highly Cited
1997
Highly Cited
1997
OBJECTIVE The aim of this study was to evaluate the immediate and long-term results in a retrospective series of patients with… Expand