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aplidine

Known as: N-[1-(1,2-Dioxopropyl)-L-prolyl]didemnin A, DDB, APLD 
A cyclic depsipeptide isolated from the marine tunicate Aplidium albicans. Plitidepsin displays a broad spectrum of antitumor activities, inducing… 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (1)

Depsipeptides
NCIt Antineoplastic Agent Terminology

Narrower (1)

aplidin

Papers overview

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2010
2010
Antifibrotic effects of ZK14, a novel nitric oxide-donating biphenyldicarboxylate derivative, on rat HSC-T6 cells and CCl4-induced hepatic fibrosis
AbstractAim:To study the pharmacologic effect of ZK14, a novel nitric oxide-donating biphenyldicarboxylate (DDB) derivative, on… 
2008
2008
DDB Life Style Study Data Disk for Use with Consumer Behavior: Building Marketing Strategy -10/E (CD)
Review
2008
Review
2008
Treatment of polycystic liver disease with resection-fenestration and a new classification.
AIM To evaluate outcomes in patients with autosomal dominant polycyst liver disease (APLD) treated by combined hepatic resection… 
2006
2006
The anti-hepatitis drug DDB chemosensitizes multidrug resistant cancer cells in vitro and in vivo by inhibiting P-gp and enhancing apoptosis
SummaryPurpose: DDB (dimethyl-4,4′-dimethoxy-5,6,5′6′-dimethylene dioxybiphenyl-2,2′-dicarboxylate) is a synthetic… 
2001
2001
Metabolism of dimethyl-4,4'-dimethoxy-5,6,5',6'-dimethylene dioxybiphenyl-2,2'-dicarboxylate (DDB) by human liver microsomes: characterization of metabolic pathways and of cytochrome P450 isoforms…
Metabolic fate of DDB and identification of P450 isozymes involved in the metabolism of DDB were investigated in human liver… 
2000
2000
Antifibrotic effects of the methanol extract of Polygonum aviculare in fibrotic rats induced by bile duct ligation and scission.
The antifibrotic effect of the methanol extract from Polygonum aviculare (PA), Artemisia capillaris (AC) and an aqueous solution… 
1995
1995
An Economic Evaluation of a Clinical Trial to Compare Automated Percutaneous Lumbar Discectomy With Microdiscectomy in the Treatment of Contained Lumbar Disc Herniation
Study Design A cost-effectiveness study of automated percutaneous lumbar discectomy (APLD) vs. microdiscectomy in the treatment… 
1992
1992
The influence of automated percutaneous lumbar discectomy (APLD) on the biomechanics of the lumbar intervertebral disc. An experimental study.
Twenty human lumbar motion segments were prepared and tested in an electromechanical materials testing machine in order to… 
1989
1989
Induction of a novel damage-specific DNA binding protein correlates with enhanced DNA repair in primate cells.
Pretreatment of mammalian cell with DNA-damaging agents, such as UV light or mitomycin C, but not the tumor promoter 12-O… 
1982
1982
Pharmacological properties of dibenzo[a,c]cyclooctene derivatives isolated from Fructus Schizandrae chinensis. I. Interaction with rat liver cytochrome P-450 and inhibition of xenobiotic metabolism…
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