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anacetrapib
A cholesteryl ester transfer protein (CETP) inhibitor with hypocholesterolemic properties. Anacetrapib reduces the transfer of cholesteryl ester from…
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National Institutes of Health
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Related topics
Related topics
3 relations
Broader (2)
Anticholesteremic Agents
Oxazolidinones
MK 0859
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2018
Highly Cited
2018
Effects of Anacetrapib in Patients With Atherosclerotic Vascular Disease
L. Bowman
,
J. Hopewell
,
F. Chen
,
K. Wallendszus
,
W. Stevens
2018
Corpus ID: 3579401
Highly Cited
2017
Highly Cited
2017
Effects of Anacetrapib in Patients with Atherosclerotic Vascular Disease
Louise Bowman
,
J. Hopewell
,
+8 authors
M. Landray
New England Journal of Medicine
2017
Corpus ID: 263594530
BACKGROUND Patients with atherosclerotic vascular disease remain at high risk for cardiovascular events despite effective statin…
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Review
2014
Review
2014
Recent advances in pharmacotherapy for hypertriglyceridemia.
A. Sahebkar
,
G. Chew
,
G. Watts
Progress in lipid research
2014
Corpus ID: 43840075
Highly Cited
2014
Highly Cited
2014
Anacetrapib reduces progression of atherosclerosis, mainly by reducing non-HDL-cholesterol, improves lesion stability and adds to the beneficial effects of atorvastatin
S. Kühnast
,
Sam J. L. van der Tuin
,
+10 authors
H. Princen
European Heart Journal
2014
Corpus ID: 15880308
The present study is the first intervention study in a well-established, translational mouse model for hyperlipidaemia and…
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Highly Cited
2011
Highly Cited
2011
Preparative scale synthesis of the biaryl core of anacetrapib via a ruthenium-catalyzed direct arylation reaction: unexpected effect of solvent impurity on the arylation reaction.
S. Ouellet
,
A. Roy
,
+4 authors
I. Davies
Journal of Organic Chemistry
2011
Corpus ID: 45651033
In this report, we disclose our findings regarding the remarkable effect of a low-level impurity found in the solvent used for a…
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Highly Cited
2010
Highly Cited
2010
Safety of anacetrapib in patients with or at high risk for coronary heart disease.
C. Cannon
,
Sukrut Shah
,
+10 authors
P. Barter
New England Journal of Medicine
2010
Corpus ID: 8968652
BACKGROUND Anacetrapib is a cholesteryl ester transfer protein inhibitor that raises high-density lipoprotein (HDL) cholesterol…
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Highly Cited
2010
Highly Cited
2010
Cholesterol Efflux Potential and Antiinflammatory Properties of High-Density Lipoprotein After Treatment With Niacin or Anacetrapib
L. Yvan-Charvet
,
J. Kling
,
+6 authors
A. Tall
Arteriosclerosis, Thrombosis and Vascular Biology
2010
Corpus ID: 3090610
Objective—To examine the effects of treatments with niacin or anacetrapib (an inhibitor of cholesteryl ester transfer protein) on…
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Highly Cited
2009
Highly Cited
2009
Drug Discovery Using Chemical Systems Biology: Identification of the Protein-Ligand Binding Network To Explain the Side Effects of CETP Inhibitors
Li Xie
,
Jerry Li
,
Lei Xie
,
P. Bourne
PLoS Comput. Biol.
2009
Corpus ID: 11260110
Systematic identification of protein-drug interaction networks is crucial to correlate complex modes of drug action to clinical…
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Highly Cited
2008
Highly Cited
2008
Torcetrapib-induced blood pressure elevation is independent of CETP inhibition and is accompanied by increased circulating levels of aldosterone
M. J. Forrest
,
D. Bloomfield
,
+21 authors
R. Woltmann
British Journal of Pharmacology
2008
Corpus ID: 4550953
Inhibition of cholesteryl ester transfer protein (CETP) with torcetrapib in humans increases plasma high density lipoprotein (HDL…
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Highly Cited
2008
Highly Cited
2008
Multiple‐Dose Pharmacodynamics and Pharmacokinetics of Anacetrapib, a Potent Cholesteryl Ester Transfer Protein (CETP) Inhibitor, in Healthy Subjects
R. Krishna
,
A. Bergman
,
+20 authors
J. Wagner
Clinical pharmacology and therapy
2008
Corpus ID: 33106760
Cholesteryl ester transfer protein (CETP) is a plasma protein that catalyzes the heteroexchange of cholesteryl esters from high…
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