amorphadiene
National Institutes of Health
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To date, the major host organisms used for the heterologous production of terpenoids, i.e., E. coli and S. cerevisiae, do not…
Purpose: The low content of artemisinin related to the biosynthetic pathway is influenced by the role of certain enzymes in the…
8-Methoxy-γ-humulene, (E)-8-methoxy-β-farnesene, 12-methoxy-β-sesquiphellandrene and 12-methoxyzingiberene can be synthesised in…
Artemisinin-based combination therapy (ACT) forms the frontline treatment of malaria. Artemisinin, an endoperoxide…
The pathway of 2-methyl-D-erythritol-4-phosphate (MEP) is the exclusive isoprenoid precursor biosynthetic pathway in Escherichia…
Enhancement of the cellular exportation of heterologous compounds is an important aspect to improve the product yield in…
Engineering biological systems and organisms is a costly team effort and may be incompatible with an open-source regulatory…
The natural plant product artemisinin is highly effective against multidrugresistant strains of malaria. However, obtaining…