amorphadiene

 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2003-2018
024620032018

Papers overview

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2016
2016
Metabolic engineering aims at altering cellular metabolism to produce valuable products at high yields and titers. Achieving high… (More)
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2013
Highly Cited
2013
Heterologous pathways used in metabolic engineering may produce intermediates toxic to the cell. Dynamic control of pathway… (More)
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2013
2013
Genetically engineered microbes have been intensively investigated as a means for the cost-effective production of isoprenoids… (More)
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2012
Highly Cited
2012
Malaria, caused by Plasmodium sp, results in almost one million deaths and over 200 million new infections annually. The World… (More)
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2009
Highly Cited
2009
The introduction or creation of metabolic pathways in microbial hosts has allowed for the production of complex chemicals of… (More)
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2008
2008
Saccharomyces cerevisiae utilizes several regulatory mechanisms to maintain tight control over the intracellular level of… (More)
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2007
Highly Cited
2007
Amorphadiene, a sesquiterpene precursor to the anti-malarial drug artemisinin, is synthesized by the cyclization of farnesyl… (More)
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2006
Highly Cited
2006
Malaria is a global health problem that threatens 300–500 million people and kills more than one million people annually. Disease… (More)
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2006
Highly Cited
2006
Reconstructing synthetic metabolic pathways in microbes holds great promise for the production of pharmaceuticals in large-scale… (More)
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2003
Highly Cited
2003
Isoprenoids are the most numerous and structurally diverse family of natural products. Terpenoids, a class of isoprenoids often… (More)
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