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amorpha-4,11-diene synthase

National Institutes of Health

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Highly Cited
2012
Highly Cited
2012
Plants of Artemisia annua produce artemisinin, a sesquiterpene lactone widely used in malaria treatment. Amorpha-4,11-diene… Expand
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2012
2012
Artemisia annua L. is the only commercial source of the widely used antimalarial compound artemisinin. Biosynthesis of… Expand
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Highly Cited
2011
Highly Cited
2011
Artemisinin, an endoperoxide sesquiterpene lactone, is a novel antimalarial natural product isolated from Artemisia annua L… Expand
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2011
2011
Artemisia annua L. produces small amounts of the sesquiterpenoid artemisinin, which is used for treatment of malaria. A worldwide… Expand
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Highly Cited
2009
Highly Cited
2009
Amorpha-4,11-diene synthase (ADS) of Artemisia annua catalyzes the conversion of farnesyl diphosphate into amorpha-4,11-diene… Expand
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2009
2009
Aims:  To investigate the effect of the yeast‐conform variant of the Artemisia annua gene encoding for amorpha‐4,11‐diene… Expand
Highly Cited
2009
Highly Cited
2009
This paper provides evidence that salicylic acid (SA) can activate artemisinin biosynthesis in Artemisia annua L. Exogenous… Expand
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2008
2008
Amorpha-4,11-diene synthase (ADS) of Artemisia annua L. is a sesquiterpene cyclase that catalyzes the conversion of farnesyl… Expand
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Highly Cited
2006
Highly Cited
2006
Cyclization of farnesyl diphosphate into amorpha-4,11-diene by amorpha-4,11-diene synthase (ADS) initiates biosynthesis of… Expand
Highly Cited
2004
Highly Cited
2004
A quantitative assay for the analysis of sesquiterpene synthases, wherein each reaction mixture is formulated in glass gas… Expand