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amorpha-4,11-diene synthase

 
National Institutes of Health

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2018
2018
Amorpha-4,11-diene synthase (ADS) cyclizes the substrate farnesyl pyrophosphate to produce amorpha-4,11-diene as a major product… Expand
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Highly Cited
2012
Highly Cited
2012
Plants of Artemisia annua produce artemisinin, a sesquiterpene lactone widely used in malaria treatment. Amorpha-4,11-diene… Expand
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2012
2012
Artemisia annua L. is the only commercial source of the widely used antimalarial compound artemisinin. Biosynthesis of… Expand
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Highly Cited
2011
Highly Cited
2011
Artemisinin, an endoperoxide sesquiterpene lactone, is a novel antimalarial natural product isolated from Artemisia annua L… Expand
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2011
2011
Artemisia annua L. produces small amounts of the sesquiterpenoid artemisinin, which is used for treatment of malaria. A worldwide… Expand
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Highly Cited
2010
Highly Cited
2010
The relationship between the transition to budding and flowering in Artemisia annua and the production of the antimalarial… Expand
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Highly Cited
2009
Highly Cited
2009
Amorpha-4,11-diene synthase (ADS) of Artemisia annua catalyzes the conversion of farnesyl diphosphate into amorpha-4,11-diene… Expand
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Highly Cited
2009
Highly Cited
2009
This paper provides evidence that salicylic acid (SA) can activate artemisinin biosynthesis in Artemisia annua L. Exogenous… Expand
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2008
2008
Amorpha-4,11-diene synthase (ADS) of Artemisia annua L. is a sesquiterpene cyclase that catalyzes the conversion of farnesyl… Expand
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2006
2006
Cyclization of farnesyl diphosphate into amorpha-4,11-diene by amorpha-4,11-diene synthase (ADS) initiates biosynthesis of… Expand
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