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amopyroquine

Known as: 4-((7-chloro-4-quinolyl)amino)-alpha-1-pyrrolidinyl-o-cresol, amopyroquin 
National Institutes of Health

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Aminoquinolines

Papers overview

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2011
2011
Buchwald reaction as the key step for the synthesis of metabolically more stable analogs of amodiaquine.
1994
1994
Pharmacokinetics and metabolism of amopyroquin after administration of two doses of 6 mg/kg im 24 h apart to healthy volunteers.
Twelve healthy volunteers received two doses of amopyroquin 6 mg/kg im 24 h apart. Blood and plasma concentrations of amopyroquin… 
1993
1993
In vitro activity of monodesethylamodiaquine and amopyroquine against African isolates and clones of Plasmodium falciparum.
The in vitro activity of monodesethylamodiaquine and amopyroquine was evaluated against chloroquine-susceptible and chloroquine… 
1989
1989
Pharmacokinetics of intramuscular amopyroquin in healthy subjects and determination of a therapeutic regimen for Plasmodium falciparum malaria
The disposition of amopyroquin was investigated in 10 healthy volunteers after a single 2-mg/kg (body weight) intramuscular dose… 
1988
1988
Disposition of amopyroquin in rats and rabbits and in vitro activity against Plasmodium falciparum
The disposition of amopyroquin was studied in rats after a single 50-mg/kg (body weight) oral dose of amopyroquin base. After a… 
1974
1974
Assessment of causal prophylactic activity in Plasmodium berghei yoelii and its value for the development of new antimalarial drugs.
The causal prophylactic activity of several reference and experimental antimalarial compounds was assessed in sporozoite-induced… 
1963
1963
AMOPYROQUIN (PROPOQUIN) IN RHEUMATOID ARTHRITIS.
A controlled, double-blind trial of amopyroquin vs. placebo has been completed in 15 patients with active, classical or definite… 
1963
1963
A DOUBLE-BLIND COMPARISON OF THE ANTI-RHEUMATIC PROPERTIES OF AMOPYROQUIN-HCI (PROPOQUIN) AND CHLOROQUINE-DIPHOSPHATE.
Propoquin and chloroquine were given in equal doses to 25 rheumatoid patients for 3 to 5 months. No clinically or statistically… 
1962
1962
Intramuscular amopyroquin for acute malaria.
1958
1958
Laboratory studies on amopyroquin (propoquin), an antimalarial compound.
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