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ammodytoxin A

National Institutes of Health

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Viper Venoms

Papers overview

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2012
2012
A recent evaluation of the lethal potencies of ammodytoxins.
2009
2009
A Neurotoxic Secretory Phospholipase A2 Induces Apoptosis in Motoneuron‐like Cells
Ammodytoxin A (AtxA) is a presynaptically neurotoxic secretory phospholipase A2 from snake venom. The aim of this study was to… 
2007
2007
Restoration of enzymatic activity in a Ser-49 phospholipase A2 homologue decreases its Ca(2+)-independent membrane-damaging activity and increases its toxicity.
Ammodytin L (AtnL) is a Ser-49 secretory phospholipase A2 (sPLA2) homologue with myotoxic activity. By analogy to the Lys-49… 
2006
2006
The C-terminal and beta-wing regions of ammodytoxin A, a neurotoxic phospholipase A2 from Vipera ammodytes ammodytes, are critical for binding to factor Xa and for anticoagulant effect.
2006
2006
Binding to the high-affinity M-type receptor for secreted phospholipases A(2) is not obligatory for the presynaptic neurotoxicity of ammodytoxin A.
2004
2004
Basic amino acid residues in the beta-structure region contribute, but not critically, to presynaptic neurotoxicity of ammodytoxin A.
2003
2003
Identification of a novel binding site for calmodulin in ammodytoxin A, a neurotoxic group IIA phospholipase A2.
The molecular mechanism of the presynaptic neurotoxicity of snake venom phospholipases A2 (PLA2s) is not yet fully elucidated… 
2002
2002
mRNA secondary structure can greatly affect production of recombinant phospholipase A(2) toxins in bacteria.
1993
1993
Expression of fully active ammodytoxin A, a potent presynaptically neurotoxic phospholipase A2, in Escherichia coli
1986
1986
Amino-acid sequence of ammodytoxin B partially reveals the location of the site of toxicity of ammodytoxins.
The complete amino-acid sequence of ammodytoxin B, a presynaptically toxic phospholipase A2 isolated from Vipera ammodytes… 
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