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ammodytoxin A

National Institutes of Health

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Viper Venoms

Papers overview

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2010
2010
Comparative structural studies of two natural isoforms of ammodytoxin, phospholipases A2 from Vipera ammodytes ammodytes which differ in neurotoxicity and anticoagulant activity.
2008
2008
A presynaptically toxic secreted phospholipase A2 is internalized into motoneuron-like cells where it is rapidly translocated into the cytosol.
2008
2008
Neurotoxicity of Ammodytoxin A in the Envenoming Bites of Vipera Ammodytes Ammodytes
Envenoming bites by Vipera ammodytes ammodytes (the long-nosed viper) can cause life-threatening neurotoxicity, particularly in… 
2008
2008
Mapping the structural determinants of presynaptic neurotoxicity of snake venom phospholipases A2.
2007
2007
Restoration of enzymatic activity in a Ser-49 phospholipase A2 homologue decreases its Ca(2+)-independent membrane-damaging activity and increases its toxicity.
Ammodytin L (AtnL) is a Ser-49 secretory phospholipase A2 (sPLA2) homologue with myotoxic activity. By analogy to the Lys-49… 
2006
2006
The C-terminal and beta-wing regions of ammodytoxin A, a neurotoxic phospholipase A2 from Vipera ammodytes ammodytes, are critical for binding to factor Xa and for anticoagulant effect.
2003
2003
Identification of a novel binding site for calmodulin in ammodytoxin A, a neurotoxic group IIA phospholipase A2.
The molecular mechanism of the presynaptic neurotoxicity of snake venom phospholipases A2 (PLA2s) is not yet fully elucidated… 
2002
2002
mRNA secondary structure can greatly affect production of recombinant phospholipase A(2) toxins in bacteria.
2000
2000
Charge reversal of ammodytoxin A, a phospholipase A2-toxin, does not abolish its neurotoxicity.
The positive charge concentrated at the C-terminal region of ammodytoxin (Atx) A, which is involved in presynaptic toxicity, has… 
Highly Cited
1985
Highly Cited
1985
Ammodytoxin A, a highly lethal phospholipase A2 from Vipera ammodytes ammodytes venom.
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