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A series of novel thiourea α-aminophosphonate derivatives containing DHA structure was designed and synthesized as antitumor… Expand We are reporting herein for the first time the synthesis of α-aminophosphonates containing Indazole moiety in two steps. In the… Expand Starting from benzaldehyde 1, the title compounds 8 were synthesized in six steps. Benzaldehyde 1 was reacted with ammonium… Expand Diaryl esters of alpha-aminophosphonates are a group of low molecular weight inhibitors of serine proteases. For over 30 years… Expand Aza-Michael reaction of ammonia, aliphatic, aromatic and optically active amines to an alpha,beta-unsaturated imine derived from… Expand Starting from (substituted-)benzaldehydes, the title compounds 6 were synthesized through five step reactions. Benzaldehydes were… Expand Target compounds 8 were obtained by the reaction of alkyl 2-cyano-3,3-dimethylthioacrylate or cyarylamide (7a-7e) and alpha… Expand Commercially available magnesium perchlorate is reported as an extremely efficient catalyst for the synthesis of alpha… Expand The kinetics of inhibition of dialkylglycine decarboxylase by five aminophosphonate inhibitors are presented. Two of these [(R)-1… Expand In Salmonella typhimurium, D-alanine:D-alanine ligase (ADP) (EC 184.108.40.206) is the second enzyme in the three enzyme D-alanine… Expand