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amflutizole

Known as: 4-amino-3-(3-(trifluoromethyl)phenyl)-5-isothiazole carboxylic acid 
 
National Institutes of Health

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Highly Cited
1997
Highly Cited
1997
Human xanthine oxidase was purified from breast milk. The dehydrogenase form of the enzyme, which predominates in most mammalian… Expand
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Highly Cited
1996
Highly Cited
1996
BACKGROUND: Reactive oxygen species may mediate tissue injury in inflammatory bowel disease. Aminosalicylates have antioxidant… Expand
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1994
1994
Free radical generation and release from the cerebral hemispheres of rats subjected to four-vessel occlusion elicited cerebral… Expand
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1994
1994
The growing evidence that glutamate may be an important agent mediating ischemic damage to neurons, led us to investigate the… Expand
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1994
1994
The efflux of hypoxanthine, xanthine and uric acid into cortical superfusates was studied with the cortical cup technique in the… Expand
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1991
1991
BACKGROUND Evidence supporting the role of xanthine oxidase in myocardial reperfusion injury is based on studies with… Expand
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1988
1988
We have assessed whether oxygen-derived free radicals produced by xanthine oxidase may be an important trigger mechanism in the… Expand
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1985
1985
The antihyperuricemic properties of amflutizole were investigated in studies designed to determine its efficacy and mechanisms of… Expand
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