ambruticin

Known as: 5,6-dihydroxypolyangioic acid 
A natural polyketide isolated from the myxobacteria Sorangium cellulosum with antifungal activity. Ambruticin interferes with the osmoregulatory… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1977-2018
012319772018

Papers overview

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2014
2014
Hydropyran rings are a common structural motif in reduced polyketides. Information on their biosynthetic formation and… (More)
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2009
2009
We have shown that the plant pathogen Alternaria brassicicola exhibited very high susceptibility to ambruticin VS4 and to a… (More)
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2007
2007
The polyketide ambruticin is an attractive candidate for drug development as an antifungal agent, but its mechanism of action has… (More)
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2006
2006
Ambruticin S, an antifungal cyclopropyl-pyran acid, showed curative effects against murine coccidioidal infection. Two analogs of… (More)
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2006
2006
Ambruticins and jerangolids are structurally related antifungal polyketides produced by Sorangium cellulosum strains. Comparative… (More)
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2006
2006
Ambruticins are a family of polyketides. The antifungal activity of an ambruticin, KOSN-2079, was tested in the mouse model of… (More)
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2000
2000
The myxobacterial fungicide, ambruticin, kills the yeast, Hansenula anomala, with high efficacy (MIC 0.05 microg/ml), but only… (More)
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1978
1978
Oral administration of ambruticin (W7783) (by gavage) was lifesaving in mice infected intranasally with arthrospores of… (More)
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1978
1978
Ambruticin is a cyclopropyl-pyran acid, representing a new class of antibiotics. It has a relatively broad antifungal spectrum in… (More)
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1977
1977
Ambruticin represents a new class of antibiotics isolated from a strain of Polyangium cellulosum var, fulvum, a bacterium… (More)
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