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alvimopan

Known as: alvimopan [Chemical/Ingredient], trans-3,4-dimethyl-4-(3-hydroxyphenyl) piperidine 
A synthetic trans-3,4-dimethyl-4-(3-hydroxyphenyl) piperidine with peripherally selective opioid mu receptor antagonist activity. Alvimopan is a… 
National Institutes of Health

Related topics

Related topics

5 relations

Narrower (2)

EnteregLY 246736

Broader (2)

Gastrointestinal AgentsPiperidines
alvimopan 12 MG Oral Capsule [Entereg]

Papers overview

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Review
2014
Review
2014
Effect of alvimopan on return of bowel function after robot-assisted radical cystectomy.
INTRODUCTION Alvimopan has been shown to improve time to return of bowel function in patients undergoing bowel resection. The… 
Review
2014
Review
2014
Off-label uses of alvimopan and methylnaltrexone.
PURPOSE Off-label uses of the peripheral μ-opioid receptor antagonists alvimopan and methylnaltrexone are reviewed. SUMMARY… 
2012
2012
A Statewide, Community-Based Assessment of Alvimopan's Effect on Surgical Outcomes
Objective: Alvimopan was approved by the Food and Drug Administration in May 2008 and has been shown to accelerate… 
Review
2012
Review
2012
Role of alvimopan (entereg) in gastrointestinal recovery and hospital length of stay after bowel resection.
PURPOSE Postoperative ileus (POI) can delay gastrointestinal (GI) recovery after bowel resection. Alvimopan (Entereg), a… 
Review
2011
Review
2011
The Effect of Alvimopan on Recovery After Laparoscopic Segmental Colectomy
BACKGROUND: Alvimopan, a peripherally acting &mgr;-opioid receptor antagonist, was recently approved for the reduction of… 
2011
2011
Does Alvimopan Enhance Return of Bowel Function in Laparoscopic Right Colectomy?
Alvimopan, a peripherally acting Mu-opioid receptor antagonist, has been shown to enhance recovery of gastrointestinal (GI… 
2011
2011
Impact of alvimopan (entereg) on hospital costs after bowel resection: results from a large inpatient database.
PURPOSE Delayed gastrointestinal (GI) recovery after bowel resection is associated with longer hospital stays and increased… 
Review
2009
Review
2009
Alvimopan for postoperative ileus.
PURPOSE The efficacy, safety, pharmacology, pharmacokinetics, drug-drug interactions, and administration of alvimopan for… 
2008
2008
Alvimopan and COX‐2 inhibition reverse opioid and inflammatory components of postoperative ileus
Abstract  Our objective was to investigate the therapeutic potential of peripheral opioid antagonism with alvimopan and anti… 
Review
2002
Review
2002
Alvimopan (Adolor/GlaxoSmithKline).
Alvimopan is a potent, peripherally active, mu-opioid receptor antagonist being developed by Adolor and GlaxoSmithKline (GSK) as… 
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