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alvimopan
Known as:
alvimopan [Chemical/Ingredient]
, trans-3,4-dimethyl-4-(3-hydroxyphenyl) piperidine
A synthetic trans-3,4-dimethyl-4-(3-hydroxyphenyl) piperidine with peripherally selective opioid mu receptor antagonist activity. Alvimopan is a…
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National Institutes of Health
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Related topics
Related topics
5 relations
Narrower (2)
Entereg
LY 246736
Broader (2)
Gastrointestinal Agents
Piperidines
alvimopan 12 MG Oral Capsule [Entereg]
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Naloxegol (Movantik) for Opioid-Induced Constipation.
Journal of the American Medical Association (JAMA…
2016
Corpus ID: 205066264
2015
2015
Synthesis method of alvimopan
牛洪芬
,
封春香
,
王兴丽
2015
Corpus ID: 102770024
The invention relates to a synthesis method of alvimopan. The method comprises the steps of taking the compound A of an acetyl…
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2012
2012
Core Aspects of Clinical Development and Trials in Chronic Idiopathic Constipation
M. Harris
,
O. Daniels
2012
Corpus ID: 51841317
861 Huang SM and Woodcock J. (2009). Transporters in drug development:advancing on the Critical Path. Nat Rev Drug Discov. 2010…
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2011
2011
Alvimopan (Entereg) for the Treatment of Postoperative Ileus
Sabesan Karuppiah
,
Roberta M Farrah
2011
Corpus ID: 79583579
Use of alvimopan should be restricted to patients at a higher risk of postoperative ileus following abdominal surgeries, such as…
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2010
2010
Preparation method of alvimopan
李智
,
王颖
,
袁明旭
2010
Corpus ID: 102873347
The invention provides a preparation method of alvimopan and an intermediate for synthesizing the alvimopan. The preparation…
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Review
2009
Review
2009
Pharmacology and clinical evaluation of alvimopan
H. Xin
2009
Corpus ID: 75357063
Alvimopan,a novel and peripherally acting μ-opioid receptor antagonist,is currently under evaluation for the management of…
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Review
2008
Review
2008
Alvimopan (Entereg) for postoperative ileus.
The Medical letter on drugs and therapeutics
2008
Corpus ID: 20157565
2007
2007
Enteroscopia por pulsión. Memorias. Hemorragia gastrointestinal de origen desconocido
J. M. Blancas-Valencia
2007
Corpus ID: 208289746
2006
2006
The Impact of Postoperative Ileus and Emerging Therapies
E. Wittbrodt
2006
Corpus ID: 29243714
Postoperative ileus (POI) is a temporary impairment of gastrointestinal (GI) function that follows surgery, especially abdominal…
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Review
2005
Review
2005
Alvimopan : A peripherally selective opioid mu receptor antagonist
PharmD Monica C. Goldman
,
PharmD Elizabeth Udeh
2005
Corpus ID: 70467969
Post-operative ileus causes significant patient morbidity and is a major contributor to patient discomfort and increased length…
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