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alpha-Crystallin A Chain

Known as: Crystallins, alpha A Chain, alpha Crystallin A Chain, alpha A-Crystallin 
One of the subunits of alpha-crystallins. Unlike ALPHA-CRYSTALLIN B CHAIN the expression of ALPHA-CRYSTALLIN A CHAIN is limited primarily to the lens… 
National Institutes of Health

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CRYAA geneIn BloodProcess of secretionagonists

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Solution structure and calcium-binding properties of M-crystallin, a primordial betagamma-crystallin from archaea.
Highly Cited
2009
Highly Cited
2009
Mutation analysis of CRYAA, CRYGC, and CRYGD associated with autosomal dominant congenital cataract in Brazilian families
Purpose Congenital cataracts are one of the most treatable causes of visual impairment and blindness during infancy… 
2009
2009
Regulation of αB-crystallin gene expression by the transcription factor Ets1 in breast cancer
Recent studies indicate that the small heat shock protein αB-crystallin is expressed in poor prognosis basal-like breast tumors… 
2002
2002
A positive charge preservation at position 116 of alpha A-crystallin is critical for its structural and functional integrity.
An autosomal dominant congenital cataract associated with a missense mutation, Arg-116 to Cys (R116C), in the coding sequence of… 
2002
2002
The alphaA-crystallin R116C mutant has a higher affinity for forming heteroaggregates with alphaB-crystallin.
An autosomal dominant congenital cataract in humans is associated with mutation of Arg-116 to Cys in alphaA-crystallin (alphaA… 
Highly Cited
2000
Highly Cited
2000
Link between a novel human gammaD-crystallin allele and a unique cataract phenotype explained by protein crystallography.
We describe a 5-year-old boy with a unique congenital cataract caused by deposition of numerous birefringent, pleiochroic and… 
Highly Cited
2000
Highly Cited
2000
Molecular basis of a progressive juvenile-onset hereditary cataract.
In a recent paper, patients with a progressive juvenile-onset hereditary cataract have been reported to have a point mutation in… 
Highly Cited
2000
Highly Cited
2000
A 5-base insertion in the γC-crystallin gene is associated with autosomal dominant variable zonular pulverulent cataract
Abstract. A seven-generation family with 30 members affected by highly variable autosomal dominant zonular pulverulent cataracts… 
Highly Cited
2000
Highly Cited
2000
Mutation of R116C results in highly oligomerized alpha A-crystallin with modified structure and defective chaperone-like function.
An autosomal dominant congenital cataract in human is associated with mutation of Arg-116 to Cys (R116C) in alpha A-crystallin… 
Highly Cited
1996
Highly Cited
1996
Conformational Properties of Substrate Proteins Bound to a Molecular Chaperone -Crystallin (*)
α-Crystallin, the major protein of the ocular lens, acts as a molecular chaperone by suppressing the nonspecific aggregation of… 
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