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alovudine

Known as: CL 184,824, 3'-fluorothymidine, 3'-fluoro-2',3'-dideoxythymidine 
A nucleoside reverse transcriptase inhibitor analog of thymidine.
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

Antiviral AgentsDideoxynucleosides

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
Quantification of intra-tumour cell proliferation heterogeneity using imaging descriptors of 18F fluorothymidine-positron emission tomography
Intra-tumour heterogeneity is a characteristic shared by all cancers. We explored the use of texture variables derived from… 
Highly Cited
2012
Highly Cited
2012
Comparison of 3′-deoxy-3′-[18F]fluorothymidine positron emission tomography (FLT PET) and FDG PET/CT for the detection and characterization of pancreatic tumours
PurposeDespite recent advances in clinical imaging modalities, differentiation of pancreatic masses remains difficult. Here, we… 
Highly Cited
2008
Highly Cited
2008
Uptake of 18F-FLT and 18F-FDG in primary head and neck cancer correlates with survival
Summary The aim of the study was to determine the practicability of 18F-FLT in tumours of the head and neck area in terms of… 
Highly Cited
2008
Highly Cited
2008
The Role of Human Nucleoside Transporters in Uptake of 3′-Deoxy-3′-fluorothymidine
3′-Deoxy-3′-fluorothymidine (FLT) is a positron emission tomography (PET) tracer used to identify proliferating tumor cells. The… 
Highly Cited
2007
Highly Cited
2007
Early Response Assessment Using 3′-Deoxy-3′-[18F]Fluorothymidine-Positron Emission Tomography in High-Grade Non-Hodgkin's Lymphoma
Purpose: To evaluate 3′-deoxy-3′-[18F]fluorothymidine-positron emission tomography (FLT-PET) for early monitoring response of… 
2007
2007
Functional diagnosis of residual lymphomas after radiochemotherapy with positron emission tomography comparing FDG- and FLT-PET
Positron emission tomography (PET) using 2-deoxy-2-[18F]fluoro-d-glucose (FDG) is used as a functional imaging technique for the… 
Highly Cited
2006
Highly Cited
2006
Use of 3′-deoxy-3′-[18F]fluorothymidine PET to monitor early responses to radiation therapy in murine SCCVII tumors
Purpose3′-Deoxy-3′-[18F]fluorothymidine (FLT) is a promising new radiopharmaceutical for imaging cell proliferation. We evaluated… 
Highly Cited
2004
Highly Cited
2004
Metabolism of 3'-deoxy-3'-[F-18]fluorothymidine in proliferating A549 cells: validations for positron emission tomography.
Review
2004
Review
2004
New nucleoside reverse transcriptase inhibitors for the treatment of HIV infections.
  • M. Otto
  • Current opinion in pharmacology (Print)
  • 2004
  • Corpus ID: 23293362
Highly Cited
1990
Highly Cited
1990
Direct comparisons of inhibitor sensitivities of reverse transcriptases from feline and human immunodeficiency viruses
The sensitivities of reverse transcriptases (RTs) from feline immunodeficiency virus (FIV) and human immunodeficiency virus type… 
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