alkaloid biosynthetic process

Known as: alkaloid formation, alkaloid biosynthesis, alkaloid anabolism 
The chemical reactions and pathways resulting in the formation of alkaloids, nitrogen-containing natural products which are not otherwise classified… (More)
National Institutes of Health

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Review
2013
Review
2013
The epichloae: alkaloid diversity and roles in symbiosis with grasses.
Epichloae (Epichloë and Neotyphodium species; Clavicipitaceae) are fungi that live in systemic symbioses with cool-season grasses… (More)
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Highly Cited
2008
Highly Cited
2008
Microbial production of plant benzylisoquinoline alkaloids.
Benzylisoquinoline alkaloids, such as the analgesic compounds morphine and codeine, and the antibacterial agents berberine… (More)
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Review
2005
Review
2005
Synthesis and trafficking of alkaloid biosynthetic enzymes.
The biosynthesis of plant natural products involves a large number of enzymes that create and elaborate a bewildering array of… (More)
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Highly Cited
2005
Highly Cited
2005
Evidence for the monophyletic evolution of benzylisoquinoline alkaloid biosynthesis in angiosperms.
Benzylisoquinoline alkaloids (BIAs) consist of more than 2500 diverse structures largely restricted to the order Ranunculales and… (More)
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Highly Cited
2004
Highly Cited
2004
Zinc finger proteins act as transcriptional repressors of alkaloid biosynthesis genes in Catharanthus roseus.
In Catharanthus roseus cell suspensions, the expression of several terpenoid indole alkaloid biosynthetic genes, including two… (More)
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Highly Cited
2004
Highly Cited
2004
Molecular cloning and characterization of norcoclaurine synthase, an enzyme catalyzing the first committed step in benzylisoquinoline alkaloid biosynthesis.
(S)-Norcoclaurine synthase (NCS) (EC 4.2.1.78) catalyzes the condensation of 3,4-dihydroxyphenylethylamine (dopamine) and 4… (More)
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2003
2003
(R,S)-Reticuline 7-O-methyltransferase and (R,S)-norcoclaurine 6-O-methyltransferase of Papaver somniferum - cDNA cloning and characterization of methyl transfer enzymes of alkaloid biosynthesis in…
S-Adenosyl-L-methionine:(R,S)-reticuline 7-O-methyltransferase converts reticuline to laudanine in tetrahydrobenzylisoquinoline… (More)
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Highly Cited
2001
Highly Cited
2001
Metabolic engineering of plant alkaloid biosynthesis.
Plant alkaloids, one of the largest groups of natural products, provide many pharmacologically active compounds. Several genes in… (More)
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Highly Cited
2000
Highly Cited
2000
Indole alkaloid biosynthesis in Catharanthus roseus: new enzyme activities and identification of cytochrome P450 CYP72A1 as secologanin synthase.
The molecular characterization of CYP72A1 from Catharanthus roseus (Madagascar periwinkle) was described nearly a decade ago, but… (More)
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Highly Cited
1999
Highly Cited
1999
Multicellular compartmentation of catharanthus roseus alkaloid biosynthesis predicts intercellular translocation of a pathway intermediate
In situ RNA hybridization and immunocytochemistry were used to establish the cellular distribution of monoterpenoid indole… (More)
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