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alglucerase
Known as:
alglucerase [Chemical/Ingredient]
National Institutes of Health
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Related topics
Related topics
6 relations
Drug Allergy
Enzymatic Activity [MoA]
GLUCOSYLCERAMIDASE
Liver diseases
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Transformation in pretreatment manifestations of Gaucher disease type 1 during two decades of alglucerase/imiglucerase enzyme replacement therapy in the International Collaborative Gaucher Group…
P. Mistry
,
Julie L. Batista
,
+10 authors
N. Weinreb
American journal of hematology/oncology
2017
Corpus ID: 4857670
This study tests the hypothesis that the prevalence of severe clinical manifestations in Gaucher disease type 1 (GD1) patients at…
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Highly Cited
2009
Highly Cited
2009
Dose-response relationships for enzyme replacement therapy with imiglucerase/alglucerase in patients with Gaucher disease type 1
G. Grabowski
,
K. Kacena
,
+7 authors
S. Dahl
Genetics in Medicine
2009
Corpus ID: 11584281
Purpose: To determine whether enzyme therapy with imiglucerase/alglucerase demonstrates dose-response relationships with doses…
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Highly Cited
1999
Highly Cited
1999
Immunosurveillance of alglucerase enzyme therapy for Gaucher patients: induction of humoral tolerance in seroconverted patients after repeat administration.
M. Rosenberg
,
W. Kingma
,
M. A. Fitzpatrick
,
S. Richards
Blood
1999
Corpus ID: 23615041
Alglucerase, a macrophage-targeted enzyme replacement therapy for Gaucher disease, has been successfully used for several years…
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1997
1997
8 Enzyme replacement therapy for Gaucher's disease
E. Beutler
1997
Corpus ID: 72009607
Highly Cited
1997
Highly Cited
1997
Differential effects of enzyme supplementation therapy on manifestations of type 1 Gaucher disease.
C. Hollak
,
E. Corssmit
,
+4 authors
M. V. van Oers
American Journal of Medicine
1997
Corpus ID: 10603985
Highly Cited
1996
Highly Cited
1996
Therapeutic delivery of proteins to macrophages: implications for treatment of Gaucher's disease
P. Mistry
,
E. Wraight
,
T. Cox
The Lancet
1996
Corpus ID: 32397456
Highly Cited
1994
Highly Cited
1994
Low-dose enzyme replacement therapy for Gaucher's disease: effects of age, sex, genotype, and clinical features on response to treatment.
A. Zimran
,
D. Elstein
,
+6 authors
A. Abrahamov
American Journal of Medicine
1994
Corpus ID: 9531328
Highly Cited
1994
Highly Cited
1994
Enzyme replacement treatment in type 1 and type 3 Gaucher's disease
B. Bembi
,
E. Agosti
,
+4 authors
F. Baralle
The Lancet
1994
Corpus ID: 40750785
Highly Cited
1993
Highly Cited
1993
Enzyme therapy in Gaucher disease type 1: dosage efficacy and adverse effects in 33 patients treated for 6 to 24 months.
G. Pastores
,
A. Sibille
,
G. Grabowski
Blood
1993
Corpus ID: 28193446
Gaucher disease is the most frequent lysosomal storage disease and the most prevalent genetic disease among the Ashkenazi Jews (q…
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Highly Cited
1992
Highly Cited
1992
A less costly regimen of alglucerase to treat Gaucher's disease.
M. Figueroa
,
B. Rosenbloom
,
+5 authors
E. Beutler
New England Journal of Medicine
1992
Corpus ID: 8079691
BACKGROUND Alglucerase (Ceredase) provides effective enzyme-replacement treatment for patients with Gaucher's disease, but at the…
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