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alglucerase

Known as: alglucerase [Chemical/Ingredient] 
 
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Purpose: To determine whether enzyme therapy with imiglucerase/alglucerase demonstrates dose-response relationships with doses… Expand
2004
2004
A marked elevation in plasma chitotriosidase (chitinase) activity has recently been observed in patients with Gaucher disease… Expand
Highly Cited
1999
Highly Cited
1999
Alglucerase, a macrophage-targeted enzyme replacement therapy for Gaucher disease, has been successfully used for several years… Expand
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Highly Cited
1996
Highly Cited
1996
OBJECTIVES The incidence and severity of growth retardation in children with type 1 Gaucher disease and the response to enzyme… Expand
1996
1996
Gaucher disease is an autosomal-recessive disorder that is caused by a deficiency of the enzyme glucocerebrosidase and results in… Expand
Highly Cited
1995
Highly Cited
1995
Previous studies have shown that enzyme supplementation therapy with alglucerase for type 1 Gaucher's disease is effective at… Expand
Highly Cited
1995
Highly Cited
1995
One hundred nineteen patients with Gaucher disease were examined in the past 13 years. Of these 45 were examined 3 or more times… Expand
Highly Cited
1993
Highly Cited
1993
Gaucher disease is the most frequent lysosomal storage disease and the most prevalent genetic disease among the Ashkenazi Jews (q… Expand
Highly Cited
1993
Highly Cited
1993
Mannose-terminated glucocerebrosidase (alglucerase; Ceredase) was designed for enzyme replacement therapy in Gaucher disease to… Expand
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Highly Cited
1992
Highly Cited
1992
BACKGROUND Alglucerase (Ceredase) provides effective enzyme-replacement treatment for patients with Gaucher's disease, but at the… Expand