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alglucerase

Known as: alglucerase [Chemical/Ingredient] 
National Institutes of Health

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Drug AllergyEnzymatic Activity [MoA]GLUCOSYLCERAMIDASELiver diseases

Papers overview

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2012
2012
Alglucerase
SummaryGaucher disease is caused by a deficiency of glucocerebrosidase. It is the first lysosomal storage disorder for which… 
2011
2011
[Therapeutic targets in Gaucher's disease].
2008
2008
[Enzyme replacement therapy for Gaucher's Disease].
Rekombinant hergestellte Glucocerebrosidase (Imiglucerase, Cerezyme®) zur Therapie der lysosomalen Speicherkrankheit Morbus… 
1998
1998
[Uveitis masquerade syndrome in Gaucher disease. Causal treatment by alglucerase substitution therapy].
BACKGROUND Gaucher's disease, a sphingolipidose transmitted by autosomal-recessive inheritance, is caused by a deficiency of the… 
1997
1997
Should repeated partial splenectomy be attempted in patients with hematological diseases? Technical pitfalls and causes of failure in Gaucher's disease.
1997
1997
[Alglucerase treatment of type I Gaucher's disease. Preliminary results in Spain. Spanish Group on Gaucher's Disease].
AIM To evaluate the efficacy of the treatment with alglucerase (Ceredase) in spanish patients diagnosed of Gaucher disease type 1… 
1996
1996
Tissue distribution and half-lifes of intravenously administered alglucerase
  • Y. Xu
  • 1996
  • Corpus ID: 57788006
1995
1995
A biochemical and immunocytochemical study on the targeting of alglucerase in murine liver
SummaryA current hypothesis is that functional glucocerebrosidase needs to be delivered to the lysosomes of tissue macrophages to… 
1994
1994
HCG contamination of alglucerase: Clinical implications in low‐dose regimen
Alglucerase (Ceredase) is currently the treatment of choice for patients with symptomatic Gaucher disease. The contamination of… 
Review
1992
Review
1992
Alglucerase. A review of its therapeutic use in Gaucher's disease.
Alglucerase is a mannose-terminated form of human placental glucocerebrosidase, developed to treat patients with Gaucher's… 
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