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alginic acid biosynthetic process

Known as: alginic acid synthesis, alginic acid formation, alginic acid biosynthesis 
The chemical reactions and pathways resulting in the formation of alginic acid, a hydrophilic polysaccharide occurring in, for example, the cell… 
National Institutes of Health

Papers overview

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Highly Cited
2004
Highly Cited
2004
The role of polyhydroxyalkanoate biosynthesis by Pseudomonas aeruginosa in rhamnolipid and alginate production as well as stress tolerance and biofilm formation.
Pseudomonas aeruginosa is capable of synthesizing polyhydroxyalkanoic acids (PHAs) and rhamnolipids, both of which are composed… 
Highly Cited
2003
Highly Cited
2003
Crystal structure of GDP-mannose dehydrogenase: a key enzyme of alginate biosynthesis in P. aeruginosa.
The enzyme GMD from Pseudomonas aeruginosa catalyzes the committed step in the synthesis of the exopolysaccharide alginate… 
Highly Cited
1998
Highly Cited
1998
Phosphorylation-Independent Activity of the Response Regulators AlgB and AlgR in Promoting Alginate Biosynthesis in MucoidPseudomonas aeruginosa
ABSTRACT Overproduction of the capsular polysaccharide alginate appears to confer a selective advantage for Pseudomonas… 
Highly Cited
1997
Highly Cited
1997
Posttranslational control of the algT (algU)-encoded sigma22 for expression of the alginate regulon in Pseudomonas aeruginosa and localization of its antagonist proteins MucA and MucB (AlgN)
Pseudomonas aeruginosa strains associated with cystic fibrosis are often mucoid due to the copious production of alginate, an… 
Highly Cited
1996
Highly Cited
1996
Characterization of the genes coding for the putative sigma factor AlgU and its regulators MucA, MucB, MucC, and MucD in Azotobacter vinelandii and evaluation of their roles in alginate biosynthesis
The study of the biosynthesis of alginate, the exopolysaccharide produced by Azotobacter vinelandii and Pseudomonas aeruginosa… 
Highly Cited
1995
Highly Cited
1995
Regulation of the alginate biosynthesis gene algC in Pseudomonas aeruginosa during biofilm development in continuous culture
Reporter gene technology was used to observe the regulation of the alginate biosynthesis gene, algC in a mucoid strain of… 
Highly Cited
1995
Highly Cited
1995
The algT (algU) gene of Pseudomonas aeruginosa, a key regulator involved in alginate biosynthesis, encodes an alternative sigma factor (sigma E).
Chronic infection by alginate-producing (mucoid) Pseudomonas aeruginosa is the leading cause of mortality among cystic fibrosis… 
Highly Cited
1990
Highly Cited
1990
Cloning of Pseudomonas aeruginosa algG, which controls alginate structure
The biochemical mechanism by which alpha-L-guluronate (G) residues are incorporated into alginate by Pseudomonas aeruginosa is… 
Highly Cited
1987
Highly Cited
1987
Gene algD coding for GDPmannose dehydrogenase is transcriptionally activated in mucoid Pseudomonas aeruginosa
Transcriptional regulation of alginate biosynthesis by Pseudomonas aeruginosa was studied. A DNA region complementing the alg-5… 
Highly Cited
1984
Highly Cited
1984
Cloning of genes controlling alginate biosynthesis from a mucoid cystic fibrosis isolate of Pseudomonas aeruginosa
Mucoid strains of Pseudomonas aeruginosa isolated from the sputum of cystic fibrosis patients produce copious quantities of an… 
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