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albinterferon alfa-2b

Known as: Albumin-interferon alpha, Albinterferon, alb-IFN 
A long-acting, recombinant fusion polypeptide consisting of interferon alpha-2b (IFNa-2b) linked to human albumin (alb-IFN), with antiviral and… 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

AlbuminsInterferon-alpha

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Albinterferon α2b adsorption to silicone oil-water interfaces: effects on protein conformation, aggregation, and subvisible particle formation.
Silicone oil used as a lubricant in prefilled syringes has the potential to induce formation of particles in protein formulations… 
Highly Cited
2011
Highly Cited
2011
Viral clearance is associated with improved insulin resistance in genotype 1 chronic hepatitis C but not genotype 2/3
Objectives Genotype-specific associations between hepatitis C virus (HCV) and insulin resistance (IR) have been described, but a… 
Highly Cited
2010
Highly Cited
2010
Albinterferon Alfa-2b was not inferior to pegylated interferon-α in a randomized trial of patients with chronic hepatitis C virus genotype 1.
BACKGROUND & AIMS The current standard of care for patients with chronic hepatitis C virus (HCV) genotype 1 is once-weekly… 
2010
2010
Albinterferon Alfa-2b was not inferior to pegylated interferon-α in a randomized trial of patients with chronic hepatitis C virus genotype 2 or 3.
BACKGROUND & AIMS A phase 3 active-controlled study was conducted to assess the efficacy/safety of albinterferon alfa-2b (albIFN… 
Highly Cited
2009
Highly Cited
2009
An independent and prospective comparison of two commercial fibrosis marker panels (HCV FibroSURE and FIBROSpect II) during albinterferon alfa‐2b combination therapy for chronic hepatitis C
Summary.  Noninvasive markers that accurately follow changes in fibrosis may provide alternatives to liver biopsy for assessment… 
Review
2009
Review
2009
Albinterferon alfa-2b, a novel fusion protein of human albumin and human interferon alfa-2b, for chronic hepatitis C
ABSTRACT Objective: New treatment options for chronic hepatitis C (CHC) that offer improved efficacy, tolerability, and… 
Highly Cited
2008
Highly Cited
2008
Albinterferon alfa‐2b dosed every two or four weeks in interferon‐naïve patients with genotype 1 chronic hepatitis C
The efficacy and safety of albinterferon alfa‐2b (alb‐IFN), a novel recombinant protein consisting of interferon alfa‐2b… 
Highly Cited
2007
Highly Cited
2007
Albinterferon α-2b: a genetic fusion protein for the treatment of chronic hepatitis C
Treatment regimens based on the use of interferon-α (IFN-α) remain the cornerstone of therapy for chronic hepatitis C virus… 
2007
2007
Anti‐hepatitis C virus activity of albinterferon alfa‐2b in cell culture
Background:  Interferon‐based combination therapy is the standard treatment for chronic hepatitis C virus (HCV) infection. The… 
Highly Cited
2006
Highly Cited
2006
A phase 2 study to evaluate the antiviral activity, safety, and pharmacokinetics of recombinant human albumin-interferon alfa fusion protein in genotype 1 chronic hepatitis C patients.
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