aerolysin

A number of bacterial virulence factors have been observed to adopt structures similar to that of aerolysin, the principal toxin… (More)

Protein export is an essential mechanism in living cells and exported proteins are usually translocated through a protein… (More)

Paroxysmal nocturnal hemoglobinuria (PNH) is caused by a somatic mutation in the gene PIGA, which encodes an enzyme essential for… (More)

It has been proposed that the plasma membrane of many cell types contains cholesterol-sphingolipid-rich microdomains. Here, we… (More)

Aerolysin is a channel-forming toxin that binds to glycosylphosphatidylinositol (GPI)-anchored proteins, such as Thy-1, on target… (More)

Paroxysmal nocturnal hemoglobinuria (PNH) is a clonal stem cell disorder caused by a somatic mutation of the PIGA gene. The… (More)

Cells that are sensitive to the channel-forming toxin aerolysin contain surface glycoproteins that bind the toxin with high… (More)

Aerolysin is a channel-forming protein secreted by virulent Aeromonas spp. Some eucaryotic cells, including T-lymphocytes, are… (More)

A precursor-product relationship between aerolysin and a protein with a higher molecular weight was observed in culture… (More)

Conditions are defined for the production, in high titers, of an extracellular hemolytic toxin of Aeromonas hydrophila, here… (More)