adenylate cyclase activity

Known as: adenylylcyclase activity, ATP diphosphate-lyase (cyclizing) activity, ATP diphosphate-lyase (cyclizing; 3',5'-cyclic-AMP-forming) activity 
Catalysis of the reaction: ATP = 3',5'-cyclic AMP + diphosphate. [EC:4.6.1.1]
National Institutes of Health

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Highly Cited
2002
Highly Cited
2002
Neurofibromatosis type 1 (NF1) is a dominant genetic disorder characterized by multiple benign and malignant nervous system… (More)
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Highly Cited
2000
Highly Cited
2000
Atrial natriuretic peptide (ANP) receptors have been described on rodent adipocytes and expression of their mRNA is found in… (More)
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Highly Cited
1999
Highly Cited
1999
It is hypothesized that Ca2+ stimulation of calmodulin (CaM)-activated adenylyl cyclases (AC1 or AC8) generates cAMP signals… (More)
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Highly Cited
1995
Highly Cited
1995
A heptadecapeptide was identified and purified from porcine brain tissue as a ligand for an orphan heterotrimeric GTP-binding… (More)
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Highly Cited
1990
Highly Cited
1990
We have recently shown that atrial natriuretic factor (ANF) inhibits adenylate cyclase activity in rat platelets where only one… (More)
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1987
1987
Stimulation and inhibition of adenylate cyclase activity are mediated by the guanine nucleotide regulatory proteins Gs and Gi… (More)
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1984
1984
The synthetic atrial natriuretic factor (ANF) (8- 33AA ) inhibited adenylate cyclase activity in aorta washed particles… (More)
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1980
1980
In ghosts of hamster adipocytes, the regulation of adenylate cyclase (ATP: pyrophosphate lyase, cyclizing; EC 4.6.1.1) activity… (More)
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Highly Cited
1972
Highly Cited
1972
An adenylate cyclase that is activated specifically by low concentrations of dopamine has been demonstrated in homogenates of… (More)
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Highly Cited
1971
Highly Cited
1971
The effects of several prostaglandins (PG) and a highly purified preparation of cholera enterotoxin (CT) on intestinal mucosal… (More)
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