adduct

Hepatocellular carcinoma (HCC) has been known as one of the most lethal human malignancies, due to the difficulty of early… (More)

The substantia nigra in Parkinson's disease (PD) is depleted of dopaminergic neurons and contains fibrillar Lewy bodies… (More)

DNA repair genes have an important role in protecting individuals from cancer-causing agents. Polymorphisms in several DNA repair… (More)

Recent studies suggested that interruption of the interaction of advanced glycation end products (AGEs), with the signal… (More)

Hereditary genetic defects in DNA repair lead to increased risk of cancer. Polymorphisms in several DNA repair genes have been… (More)

Cigarette smoke carcinogens such as benzo[a]pyrene are implicated in the development of lung cancer. The distribution of benzo[a… (More)

There is growing evidence that oxidative stress and mitochondrial respiratory failure with attendant decrease in energy output… (More)

We have recently shown that nitric oxide or authentic endothelium-derived relaxing factor generated in a biologic system reacts… (More)

This assay of plasma lipoperoxides involves hydrolysis in dilute H3PO4 at 100 degrees C; complexation of malondialdehyde (MDA), a… (More)

Exceedingly sensitive procedures are required to detect the presence of covalent DNA adducts in humans exposed to environmental… (More)