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acetylacetoin reductase (NADH)

Known as: AACR II 
National Institutes of Health

Papers overview

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Highly Cited
2016
Highly Cited
2016
Exosomes Derived from Hypoxic Oral Squamous Cell Carcinoma Cells Deliver miR-21 to Normoxic Cells to Elicit a Prometastatic Phenotype.
Hypoxia is a common feature of solid tumors and is associated with aggressiveness and poor patient outcomes. Exosomes, initially… 
Review
2016
Review
2016
Plk1 Inhibitors in Cancer Therapy: From Laboratory to Clinics
Polo-like kinase 1 (Plk1) overexpression has been shown to occur in a wide range of tumors, prompting research and development of… 
Highly Cited
2016
Highly Cited
2016
STING Promotes the Growth of Tumors Characterized by Low Antigenicity via IDO Activation.
Cytosolic DNA sensing is an important process during the innate immune response that activates the stimulator of interferon genes… 
Highly Cited
2016
Highly Cited
2016
T-Cell Immunoglobulin and ITIM Domain (TIGIT) Associates with CD8+ T-Cell Exhaustion and Poor Clinical Outcome in AML Patients
Purpose: T-cell immunoglobulin and immunoreceptor tyrosine–based inhibitory motif (ITIM) domain (TIGIT) is a recently identified… 
Highly Cited
2016
Highly Cited
2016
Entrectinib, a Pan–TRK, ROS1, and ALK Inhibitor with Activity in Multiple Molecularly Defined Cancer Indications
Activated ALK and ROS1 tyrosine kinases, resulting from chromosomal rearrangements, occur in a subset of non–small cell lung… 
Highly Cited
2016
Highly Cited
2016
Transcriptome Analysis of Triple-Negative Breast Cancer Reveals an Integrated mRNA-lncRNA Signature with Predictive and Prognostic Value.
While recognized as a generally aggressive disease, triple-negative breast cancer (TNBC) is highly diverse in different patients… 
Highly Cited
2016
Highly Cited
2016
Plasma Circulating Tumor DNA in Pancreatic Cancer Patients Is a Prognostic Marker
Purpose: Despite recent therapeutic advances, prognosis of patients with pancreatic adenocarcinoma remains poor. Analyses from… 
Highly Cited
2016
Highly Cited
2016
Circulating DNA as a Strong Multimarker Prognostic Tool for Metastatic Colorectal Cancer Patient Management Care
Purpose: Circulating cell-free DNA (ccfDNA) is a valuable source of tumor material obtained from a simple blood sampling that… 
Highly Cited
2016
Highly Cited
2016
Myeloid-Derived Suppressor Cells Express Bruton's Tyrosine Kinase and Can Be Depleted in Tumor-Bearing Hosts by Ibrutinib Treatment.
Myeloid-derived suppressor cells (MDSC) are a heterogeneous group of immature myeloid cells that expand in tumor-bearing hosts in… 
Review
2014
Review
2014
Emerging Functions of SRSF1, Splicing Factor and Oncoprotein, in RNA Metabolism and Cancer
Serine/Arginine Splicing Factor 1 (SRSF1) is the archetype member of the SR protein family of splicing regulators. Since its… 
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