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aaptamine

Known as: 8,9-dimethoxy-1H-benzo(de)(1,6)naphthyridine 
National Institutes of Health

Related topics

Related topics

2 relations
2-methoxy-3-oxoaaptamine

Broader (1)

Naphthyridines

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
N-Demethylaaptanone, A new Congener of Aaptamine Alkaloids from the Vietnamese Marine Sponge Aaptos aaptos
A new compound, N-demethylaaptanone (5), having an oxygenated 1,6-naphthyridine core, has been isolated from the Vietnamese… 
2016
2016
An Evaluation of the Cytotoxic Effect of the Natural Product Aaptamine Against t(4;11) Leukemias
The marine environment has been shown to be a rich source of pharmacologically-active secondary metabolites. Three marine… 
2014
2014
Marine Natural Products Acting on the Acetylcholine-Binding Protein and Nicotinic Receptors: From Computer Modeling to Binding Studies and Electrophysiology
For a small library of natural products from marine sponges and ascidians, in silico docking to the Lymnaea stagnalis… 
2014
2014
Spongean alkaloids protect rat kidney cells against cisplatin-induced cytotoxicity
Nephrotoxicity is the major dose-limiting adverse effect of cisplatin (CisPt) and results from CisPt-induced damage of tubular… 
2009
2009
Aaptamine Alkaloids from the Vietnamese Sponge Aaptos sp
A series of aaptamines, including one new alkaloid (1), were isolated from the marine sponge Aaptos sp. collected in Vietnamese… 
2009
2009
Antibacterial and DPPH free radical-scavenging activities of methanolic extracts of Aaptos sp. (Marine Sponges)
This study reports on the evaluation of the antioxidant and antibacterial activities of twelve methanolic extracts (A-L) of… 
2004
2004
Antineoplastic agents. 499. Synthesis of hystatin 2 and related 1H-benzo[de][1,6]-naphthyridinium salts from aaptamine.
The marine sponge constituent aaptamine (1) has been converted to the cancer cell growth inhibitor and antibiotic designated… 
2000
2000
Synthesis of 8-methoxy-1-methyl-1H-benzo[de][1,6]naphthyridin-9-ol (Isoaaptamine) and analogues.
8-Methoxy-1-methyl-1H-benzo[de][1,6]naphthyridin-9-ol, isoaaptamine, a PKC inhibitor isolated from sponge was synthesized. The… 
1999
1999
New Regioselective Total Syntheses of Antibiotic Renierol, Renierol Acetate, and Renierol Propionate from the 5-Oxygenated Isoquinoline
New total syntheses of renierol (3), renierol acetate (4), and renierol propionate (5) were completed by the synthesis of 5… 
1990
1990
Aaptamine-new selective inhibitor of type a monoamine oxidases
The search for new monoamine oxidase (MAO) inhibitors, which selectively block the activity of MAO of types A or B, seems to be… 
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