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T lymphocyte mediated inflammation contributes to the development of T1D. Zinc Transporter 8 (ZnT8) has emerged as a target of… Expand Autoimmune Addison’s disease (AAD) associates with exceptional susceptibility to develop other autoimmune conditions, including… Expand Variant‐specific zinc transporter 8 autoantibodies (ZnT8A) against either arginine (R) or tryptophan (W) at amino acid (aa… Expand PURPOSE
Zinc transporter 8 (ZnT8) was downregulated in hypoxic retina, which could be rescued by hypoxia-inducible factor-1α (HIF… Expand OBJECTIVE
The diagnosis of autoimmune diabetes in non-obese adults is based on the detection of glutamic acid decarboxylase… Expand The zinc transporter 8 (ZnT8) was recently identified as a common autoantigen in type 1 diabetes (T1D) and inclusion of ZnT8… Expand BACKGROUND
Zinc transporter 8 (ZnT8) is a recently identified major autoantigen in type 1 diabetes, and autoantibodies to ZnT8… Expand CONTEXT
Zinc transporter 8 (ZnT8) is a newly discovered islet autoantigen in human type 1A diabetes (T1D).
The… Expand Type 1A diabetes is strongly associated with the presence of islet autoantibodies. Large scale population screening of islet… Expand Zinc transporter 8 (ZnT8) has been identified as a β-cell-specific Zinc transporter expressed in insulin-secretory granules… Expand