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Zeneca ZD 6169

Known as: ZD6169, ZD 6169, Zeneca ZD6169 
National Institutes of Health

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2 relations

Broader (2)

AmidesBenzophenones

Papers overview

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2014
2014
Evaluation of von Willebrand Factor and von Willebrand Factor Propeptide in Models of Vascular Endothelial Cell Activation, Perturbation, and/or Injury
Pharmacologically, vasoactive agents targeting endothelial and/or smooth muscle cells (SMC) are known to cause acute drug-induced… 
2013
2013
Coronary and Systemic Arterial Physiology and Immunohistochemical Markers Related to Early Coronary Arterial Lesions in Beagle Dogs Given the Potassium Channel Opener, ZD6169, or the Endothelin…
We evaluated immunohistochemistry (von Willebrand Factor [vWF] or fibrinogen) and systemic and coronary arterial physiological… 
2004
2004
Effects of ZD6169, a KATP channel opener, on neurally-mediated plasma extravasation in the rat urinary bladder induced by chemical or electrical stimulation of nerves
2004
2004
(−)-(9S)-9-(3-Bromo-4-fluorophenyl)-2,3,5,6,7,9-hexahydrothieno[3,2-b]quinolin-8(4H)-one 1,1-dioxide (A-278637), a Novel ATP-Sensitive Potassium Channel Opener: Hemodynamic Comparison to ZD-6169, WAY…
The therapeutic utility of KATP channel opening agents (KCOs) in the treatment of overactive bladder may be limited by… 
2002
2002
(−)-(9S)-9-(3-Bromo-4-fluorophenyl)-2,3,5,6,7,9-hexahydrothieno[3,2-b]quinolin-8(4H)-one 1,1-Dioxide (A-278637): A Novel ATP-Sensitive Potassium Channel Opener Efficacious in Suppressing Urinary…
Alterations in the myogenic activity of the bladder smooth muscle are thought to serve as a basis for the involuntary detrusor… 
2002
2002
N-Arylated pyrrolidin-2-ones and morpholin-3-ones as potassium channel openers.
2002
2002
(−)-(9S)-9-(3-Bromo-4-fluorophenyl)-2,3,5,6,7,9-hexahydrothieno[3,2-b]quinolin-8(4H)-one 1,1-Dioxide (A-278637): A Novel ATP-Sensitive Potassium Channel Opener Efficacious in Suppressing Urinary…
ATP-sensitive potassium (KATP) channel openers (KCOs) have been shown to inhibit spontaneous myogenic contractile activity of the… 
2001
2001
The involvement of L‐type Ca2+ channels in the relaxant effects of the ATP‐sensitive K+ channel opener ZD6169 on pig urethral smooth muscle
The effects of ZD6169, a novel ATP‐sensitive K+ channel (KATP channel) opener, were investigated on membrane currents in isolated… 
2001
2001
Fluorescence-based functional assay for sarcolemmal ATP-sensitive potassium channel activation in cultured neonatal rat ventricular myocytes.
1996
1996
N-aryl-3,3,3-trifluoro-2-hydroxy-2-methylpropanamides: KATP potassium channel openers. Modifications on the western region.
A subset of antiandrogen compounds, the N-aryl-3,3,3-trifluoro-2-hydroxy-2-methylpropanamides 1, were found to activate ATP… 
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