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Zeneca ZD 6169

Known as: ZD6169, ZD 6169, Zeneca ZD6169 
 
National Institutes of Health

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Highly Cited
2002
Highly Cited
2002
PURPOSE Adenosine triphosphate (ATP) (Sigma Chemical Co., St. Louis, Missouri) is known to contract animal as well as human… Expand
2002
2002
Alterations in the myogenic activity of the bladder smooth muscle are thought to serve as a basis for the involuntary detrusor… Expand
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Highly Cited
2001
Highly Cited
2001
Activation of ATP-sensitive potassium (K(ATP)) channels can regulate smooth muscle function through membrane potential… Expand
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Highly Cited
2000
Highly Cited
2000
PURPOSE To investigate whether intravesical oxyhemoglobin, a nitric oxide scavenger, changes bladder activity in normal rats… Expand
Highly Cited
1999
Highly Cited
1999
ATP-sensitive K+ (KATP) channels play an important role in the regulation of smooth muscle membrane potential. To investigate the… Expand
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Highly Cited
1999
Highly Cited
1999
The effects of the ATP-dependent potassium channel agonists ZD6169, celikalim, and WAY-133537 on bladder contractile function… Expand
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1999
1999
PURPOSE To investigate the urodynamic effects of the new K(ATP) channel opener, ZD6169, given intravesically, in rats with and… Expand
1998
1998
Cystometrographic recording and immunocytochemical techniques were used to examine the effects of ZD6169, an ATP-sensitive K… Expand
1997
1997
  • S. Hu, H. Kim
  • The Journal of pharmacology and experimental…
  • 1997
  • Corpus ID: 23848334
ZD6169, the S-enantiomer of the racemic N-(4-benzoylphenyl)-3,3,3-trifluoro-2-hydroxy-2-methylpropionamide , was reported to… Expand
Highly Cited
1995
Highly Cited
1995
(S)-N-(4-benzoylphenyl)-3,3,3-trifluoro-2-hydroxy-2-methyl-propionamide (ZD6169) is a novel ATP-sensitive potassium channel… Expand