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ZSTK474
Known as:
PI3K Inhibitor ZSTK474
, Phosphatidylinositol 3-kinase Inhibitor ZSTK474
An orally available, s-triazine derivative, ATP-competitive phosphatidylinositol 3-kinase (PI3K) inhibitor with potential antineoplastic activity…
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National Institutes of Health
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Related topics
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2 relations
NCIt Antineoplastic Agent Terminology
Broader (1)
Triazines
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Antiproliferative effect of ZSTK474 alone or in combination with chemotherapeutic drugs on HL60 and HL60/ADR cells
Qianxiang Zhou
,
Yali Chen
,
+7 authors
Dexin Kong
OncoTarget
2017
Corpus ID: 4965455
While chemotherapy remains to be one of the main approaches in the clinical treatment of acute myeloid leukemia (AML), multidrug…
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2016
2016
Additional file 1: Figure S1. of Class I PI3K inhibitor ZSTK474 mediates a shift in microglial/macrophage phenotype and inhibits inflammatory response in mice with cerebral ischemia/reperfusion…
Po Wang
,
Yating He
,
+4 authors
J. Hao
2016
Corpus ID: 217343534
ZSTK474 alleviates neurological deficits in the model of ischemic reperfusion. (DOCX 56 kb)
2014
2014
Phosphoinositide 3-Kinase Alpha-Dependent Regulation of Branching Morphogenesis in Murine Embryonic Lung : Evidence for a Role in Determining Morphogenic Properties of FGF 7
E. Carter
,
Gabriela Miron-Buchacra
,
+5 authors
S. Ward
2014
Corpus ID: 85505956
Branching morphogenesis is a critical step in the development of many epithelial organs. The phosphoinositide-3-kinase (PI3K…
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2012
2012
Development of an immunohistochemical protein quantification system in conjunction with tissue microarray technology for identifying predictive biomarkers for phosphatidylinositol 3-kinase inhibitors…
S. Isoyama
,
H. Yoshimi
,
+4 authors
T. Yamori
Biological and Pharmaceutical Bulletin
2012
Corpus ID: 34530987
The phosphatidylinositol 3-kinase (PI3K) pathway is frequently activated in human cancers by gain-of-function mutations of…
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2010
2010
In vitro and in vivo inhibitory effects on osteoclasts of ZSTK474, a novel phosphoinositide 3-kinase inhibitor
頭山 尚子
2010
Corpus ID: 87973792
2009
2009
Calcium-Dependent Mechanism Protein Kinase C and Is Secreted by a HMGB1 Is Phosphorylated by Classical
Y. Oh
,
J. Youn
,
+4 authors
Jeon-Soo Shin
2009
Corpus ID: 249597340
High-mobility group box 1 protein (HMGB1) has been studied as a key mediator of inflammatory diseases, including sepsis…
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