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ZNF331 gene

Known as: RITA, ZNF361, ZINC FINGER PROTEIN 463 
This gene plays a role in transcriptional regulation.
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
In response to intense stress, the tumor protein p53 (p53) tumor suppressor rapidly mounts a direct mitochondrial death program… Expand
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Highly Cited
2012
Highly Cited
2012
The tumor-suppressor p53 can induce various biological responses. Yet, it is not clear whether it is p53 in vivo promoter… Expand
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Highly Cited
2011
Highly Cited
2011
Natural killer (NK) cells are immune cells sensing and eliminating foreign, stressed, transformed, and senescent cells through… Expand
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Highly Cited
2010
Highly Cited
2010
Expression of mutant p53 correlates with poor prognosis in many tumors, therefore strategies aimed at reactivation of mutant p53… Expand
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Highly Cited
2009
Highly Cited
2009
We have previously identified the p53-reactivating compound RITA in a cell-based screen. Here, using microarray analysis, we show… Expand
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Highly Cited
2009
Highly Cited
2009
ABSTRACT The p53 tumor suppressor protein negatively regulates hypoxia-inducible factor 1α (HIF-1α). Here, we show that induction… Expand
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Highly Cited
2007
Highly Cited
2007
RAD51 is an important component of double-stranded DNA-repair mechanisms that interacts with both BRCA1 and BRCA2. A single… Expand
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Highly Cited
2007
Highly Cited
2007
In mammalian cells, the level of estrogen receptor alpha (ERalpha) is rapidly decreased upon estrogen treatment, and this… Expand
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Highly Cited
2005
Highly Cited
2005
To the editor: Issaeva et al. recently reported the discovery of a small molecule, RITA, that restores apoptosis-inducing… Expand
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Highly Cited
2004
Highly Cited
2004
In tumors that retain wild-type p53, its tumor-suppressor function is often impaired as a result of the deregulation of HDM-2… Expand
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