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ZEB1 gene

Known as: NIL2A, TCF8, Zfhep 
This gene is involved in the transcriptional repression of interleukin 2.
National Institutes of Health

Related topics

Related topics

6 relations
Homo sapiensTranscriptional RegulationZEB1 protein, humanZinc Finger E-Box-Binding Homeobox 1

Papers overview

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Highly Cited
2015
Highly Cited
2015
Upregulation of long noncoding RNA ZEB1-AS1 promotes tumor metastasis and predicts poor prognosis in hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related mortality worldwide. Despite progress in… 
Highly Cited
2015
Highly Cited
2015
ZEB1-associated drug resistance in cancer cells is reversed by the class I HDAC inhibitor mocetinostat
Therapy resistance is a major clinical problem in cancer medicine and crucial for disease relapse and progression. Therefore, the… 
Review
2013
Review
2013
ZEB/miR‐200 feedback loop: At the crossroads of signal transduction in cancer
Embryonic differentiation programs of epithelial–mesenchymal and mesenchymal–epithelial transition (EMT and MET) represent a… 
Highly Cited
2011
Highly Cited
2011
β-catenin/TCF4 complex induces the epithelial-to-mesenchymal transition (EMT)-activator ZEB1 to regulate tumor invasiveness
In most carcinomas, invasion of malignant cells into surrounding tissues involves their molecular reprogramming as part of an… 
Highly Cited
2011
Highly Cited
2011
Coordinated epigenetic repression of the miR‐200 family and miR‐205 in invasive bladder cancer
MicroRNAs (miRNA) are small noncoding RNAs commonly deregulated in cancer. The miR‐200 family (miR‐200a, ‐200b, ‐200c, ‐141 and… 
Highly Cited
2011
Highly Cited
2011
Notch-1 induces epithelial-mesenchymal transition consistent with cancer stem cell phenotype in pancreatic cancer cells.
Highly Cited
2010
Highly Cited
2010
miR-200 family and targets, ZEB1 and ZEB2, modulate uterine quiescence and contractility during pregnancy and labor
Throughout most of pregnancy, uterine quiescence is maintained by increased progesterone receptor (PR) transcriptional activity… 
Highly Cited
2006
Highly Cited
2006
Restoring E-cadherin expression increases sensitivity to epidermal growth factor receptor inhibitors in lung cancer cell lines.
The epidermal growth factor receptor (EGFR) is overexpressed in the majority of non-small cell lung cancers (NSCLC). EGFR… 
Highly Cited
1999
Highly Cited
1999
ZEB represses transcription through interaction with the corepressor CtBP.
ZEB is an active transcriptional repressor that regulates lymphocyte and muscle differentiation in vertebrates. Its homologue in… 
Highly Cited
1994
Highly Cited
1994
Displacement of an E-box-binding repressor by basic helix-loop-helix proteins: implications for B-cell specificity of the immunoglobulin heavy-chain enhancer
The activity of the immunoglobulin heavy-chain (IgH) enhancer is restricted to B cells, although it binds both B-cell-restricted… 
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