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ZD 4190

Known as: N-(4-bromo-2-fluorophenyl)-6-methoxy-7-(2-(1H-1,2,3-triazol-1-yl)ethoxy)quinazolin-4-amine, ZD-4190, ZD4190 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

QuinazolinesTriazoles

Papers overview

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2011
2011
PET imaging of early response to the tyrosine kinase inhibitor ZD4190
PurposeWe evaluated noninvasive positron emission tomography (PET) imaging for monitoring tumor response to the VEGFR-2 tyrosine… 
2007
2007
Monitoring tumor response to ZD4190 therapy with an 18F labeled angiogenesis imaging agent
10507 Background: While a number of novel therapies are being developed to inhibit the growth or survival of tumor vasculature… 
2007
2007
O162 The antiangiogenic agent ZD4190 prevents outgrowth of squamous tumor cells in a model of minimal residual cancer
Highly Cited
2003
Highly Cited
2003
Reduced capillary perfusion and permeability in human tumour xenografts treated with the VEGF signalling inhibitor ZD4190: an in vivo assessment using dynamic MR imaging and macromolecular contrast…
Review
2003
Review
2003
Angiogenesis inhibitors under study for the treatment of lung cancer.
2002
2002
Assessing perfusion and capillary permeability changes induced by a VEGF inhibitor in human tumor xenografts using macromolecular MR imaging contrast media.
Review
2001
Review
2001
Angiogenesis inhibitors in the treatment of lung cancer.
2000
2000
Inhibition of VEGF signal transduction. Identification of ZD4190.
2000
2000
Efficacy Growth Factor Signaling with Broad-Spectrum Antitumor ZD 4190 : An Orally Active Inhibitor of Vascular Endothelial
There is evidence that vascular endothelial growth factor (VEGF) contributes to solid tumor growth through the promotion of both… 
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