Yondelis
National Institutes of Health
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Trabectedin (Yondelis® [PharmaMar S.A., Madrid, Spain]) is one of the most promising agents tested in the last two decades in…
PM01183 is a novel marine-derived covalent DNA binder in clinical development. PM01183 is structurally similar to trabectedin…
Abstract The clinical impact of ET-743 (trabectedin; Yondelis) in women with leiomyosarcoma and undifferentiated uterine sarcoma…
Yondelis (trabectedin) is an antitumor ecteinascidin that binds covalently to the 2-amino group of the central guanine in the…
It was previously suggested that the peculiar mechanism of action of the novel anticancer drug Yondelis (ET-743, trabectedin) was…
The development of a simple and sensitive assay for the quantitative analysis of the marine anticancer agent Yondelis (ET-743…
“Nature distributed medicine everywhere.”Purpose of reviewThe therapeutic pharmacologic armamentarium in sarcoma is limited, and…