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YM 022

Known as: Urea, N-(2,3-dihydro-1-(2-(2-methylphenyl)-2-oxoethyl)-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl)-N'-(3-methylphenyl)-, (R)-, YM-022, YM022 
 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

BenzodiazepinesHormone Antagonists

Papers overview

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2013
2013
The dorsomedial hypothalamus mediates stress-induced hyperalgesia and is the source of the pronociceptive peptide cholecystokinin in the rostral ventromedial medulla
While intense or highly arousing stressors have long been known to suppress pain, relatively mild or chronic stress can enhance… Expand
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Highly Cited
2011
Highly Cited
2011
Gut bitter taste receptor signalling induces ABCB1 through a mechanism involving CCK.
T2Rs (bitter taste-sensing type 2 receptors) are expressed in the oral cavity to prevent ingestion of dietary toxins through… Expand
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2009
2009
Combination of sulindac and antimicrobial eradication of Helicobacter pylori prevents progression of gastric cancer in hypergastrinemic INS-GAS mice.
Helicobacter pylori infection causes severe dysplasia manifested as gastrointestinal intraepithelial neoplasia (GIN) after 28… Expand
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Highly Cited
2005
Highly Cited
2005
Luminal leptin induces rapid inhibition of active intestinal absorption of glucose mediated by sodium-glucose cotransporter 1.
The effect of leptin on glucose transport was studied in rat jejunal mucosa in Ussing chambers. Leptin was added in the luminal… Expand
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Highly Cited
2004
Highly Cited
2004
Gastrin-induced cyclooxygenase-2 expression in Barrett's carcinogenesis.
PURPOSE Cyclooxygenase (COX)-2 has been causally implicated in carcinogenesis. The evidence for increased COX-2 in the malignant… Expand
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2004
2004
Glycine-extended gastrin induces matrix metalloproteinase-1- and -3-mediated invasion of human colon cancer cells through type I collagen gel and Matrigel.
The effects of glycine-extended gastrin (G-Gly) on the invasion by colon cancer cells through stromal extracellular matrix and… Expand
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2003
2003
Impaired gastric secretion and lack of trophic responses to hypergastrinemia in M3 muscarinic receptor knockout mice.
BACKGROUND & AIMS The physiologic significance of the M(3) muscarinic receptor is unclear due to an absence of specific ligand… Expand
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2002
2002
Gastrin enhances gastric mucosal integrity through cyclooxygenase-2 upregulation in rats.
Gastrin, PGs, and growth factors have important roles in maintaining gastrointestinal mucosal integrity. Cyclooxygenases (COX-1… Expand
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1999
1999
Physiological role of cholecystokinin B/gastrin receptor in leptin secretion.
In the present study, we investigated whether cholecystokinin (CCK) or its structurally related peptide gastrin participates in… Expand
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1995
1995
Gastrin receptor antagonist YM022 prevents hypersecretion after long-term acid suppression.
Female rats were treated orally for 13 wk with YM022 (300 mumol.kg-1.day-1) and with omeprazole (400 mumol.kg-1.day-1) or… Expand
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