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YM 022
Known as:
Urea, N-(2,3-dihydro-1-(2-(2-methylphenyl)-2-oxoethyl)-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl)-N'-(3-methylphenyl)-, (R)-
, YM-022
, YM022
National Institutes of Health
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Related topics
Related topics
2 relations
Broader (2)
Benzodiazepines
Hormone Antagonists
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Gastrin promotes intestinal polyposis through cholecystokinin-B receptor-mediated proliferative signaling and fostering tumor microenvironment.
Han Ym
,
Park Jm
,
Park Sh
,
Ki Baik Hahm
,
Hong Sp
,
Kim Eh
Journal of Physiology and Pharmacology
2013
Corpus ID: 40674912
Increased serum gastrin concentrations in patients with colorectal cancer suggested the tumorigenic trophic effect of gastrin…
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2008
2008
Hypergastrinemia increases gastric epithelial susceptibility to apoptosis
S. Przemeck
,
A. Varró
,
+4 authors
D. Pritchard
Regulatory Peptides
2008
Corpus ID: 19858352
2001
2001
Effects of CCK2 receptor blockade on growth parameters in gastrointestinal tract and pancreas in rats.
M. Björkqvist
,
P. Norlén
,
+5 authors
R. Håkanson
Acta Pharmacologica et Toxicologica
2001
Corpus ID: 25896848
Gastrin has a growth-promoting effect on the oxyntic mucosa of the stomach but has been claimed also to affect other parts of the…
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1999
1999
Pharmacological analysis of CCK2 receptor antagonists using isolated rat stomach ECL cells
E. Lindström
,
M. Björkqvist
,
R. Håkanson
British Journal of Pharmacology
1999
Corpus ID: 45536591
Gastrin stimulates rat stomach ECL cells to secrete histamine and pacreastatin, a chromogranin A (CGA)‐derived peptide. The…
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1997
1997
Cholecystokinin-B/gastrin receptor blockade suppresses the activity of rat stomach ECL cells.
X. Ding
,
E. Lindström
,
R. Håkanson
Acta Pharmacologica et Toxicologica
1997
Corpus ID: 21562169
Gastrin controls the histamine- and chromogranin A-producing enterochromaffin-like (ECL) cells, the predominant endocrine cell…
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1997
1997
YM022 [(R)-1-[2,3-dihydro-1-(2'-methylphenacyl)-2-oxo-5-phenyl-1H-1,4- benzodiazepin-3-yl]-3-(3-methylphenyl)urea]: an irreversible cholecystokinin type-B receptor antagonist.
J. Dunlop
,
N. Brammer
,
N. Evans
,
C. Ennis
Biochemical Pharmacology
1997
Corpus ID: 7834041
1996
1996
Evaluation of the specificity and potency of a series of cholecystokinin-B/gastrin receptor antagonists in vivo.
X. Ding
,
R. Håkanson
Acta Pharmacologica et Toxicologica
1996
Corpus ID: 19488222
The potency and specificity of five proposed cholecystokinin-B receptor antagonists, YM022, RP73870, L-740,093, L-365,260 and…
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1996
1996
Effect of cholecystokinin-B/gastrin receptor blockade on gastric acid secretion in conscious rats.
Xi-Qin Ding
,
R. Håkanson
Acta Pharmacologica et Toxicologica
1996
Corpus ID: 35330616
Gastrin, histamine and acetylcholine are physiological stimuli of gastric acid secretion. The cholecystokinin-B/gastrin receptor…
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1995
1995
Gastrin receptor antagonist YM022 prevents hypersecretion after long-term acid suppression.
A. Nishida
,
A. Kobayashi-Uchida
,
+7 authors
Y. Nagakura
American Journal of Physiology
1995
Corpus ID: 10558092
Female rats were treated orally for 13 wk with YM022 (300 mumol.kg-1.day-1) and with omeprazole (400 mumol.kg-1.day-1) or…
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1995
1995
New 1,4-benzodiazepin-2-one derivatives as gastrin/cholecystokinin-B antagonists.
M. Satoh
,
Y. Kondoh
,
+5 authors
K. Murase
Chemical and pharmaceutical bulletin
1995
Corpus ID: 7425516
A novel series of 1-aroylmethyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one derivatives was prepared and evaluated for activity as…
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