FAQ

YM 022

Known as: Urea, N-(2,3-dihydro-1-(2-(2-methylphenyl)-2-oxoethyl)-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl)-N'-(3-methylphenyl)-, (R)-, YM-022, YM022 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1994-2017
051019942017

Related topics

Related topics

2 relations

Broader (2)

BenzodiazepinesHormone Antagonists

Related mentions per year

Related mentions per year

1947-2018
19401960198020002020
YM 022
Benzodiazepines
Hormone Antagonists

Papers overview

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2011
2011
Gut bitter taste receptor signalling induces ABCB1 through a mechanism involving CCK.
T2Rs (bitter taste-sensing type 2 receptors) are expressed in the oral cavity to prevent ingestion of dietary toxins through… (More)
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2009
2009
Combination of sulindac and antimicrobial eradication of Helicobacter pylori prevents progression of gastric cancer in hypergastrinemic INS-GAS mice.
Helicobacter pylori infection causes severe dysplasia manifested as gastrointestinal intraepithelial neoplasia (GIN) after 28… (More)
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2005
2005
Luminal leptin induces rapid inhibition of active intestinal absorption of glucose mediated by sodium-glucose cotransporter 1.
The effect of leptin on glucose transport was studied in rat jejunal mucosa in Ussing chambers. Leptin was added in the luminal… (More)
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2004
2004
Gastrin-induced cyclooxygenase-2 expression in Barrett's carcinogenesis.
PURPOSE Cyclooxygenase (COX)-2 has been causally implicated in carcinogenesis. The evidence for increased COX-2 in the malignant… (More)
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2004
2004
Glycine-extended gastrin induces matrix metalloproteinase-1- and -3-mediated invasion of human colon cancer cells through type I collagen gel and Matrigel.
The effects of glycine-extended gastrin (G-Gly) on the invasion by colon cancer cells through stromal extracellular matrix and… (More)
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2002
2002
Gastrin enhances gastric mucosal integrity through cyclooxygenase-2 upregulation in rats.
Gastrin, PGs, and growth factors have important roles in maintaining gastrointestinal mucosal integrity. Cyclooxygenases (COX-1… (More)
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1999
1999
Physiological Role of Cholecystokinin B/Gastrin Receptor in Leptin Secretion1.
In the present study, we investigated whether cholecystokinin (CCK) or its structurally related peptide gastrin participates in… (More)
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1998
1998
Mutations within the cholecystokinin-B/gastrin receptor ligand 'pocket' interconvert the functions of nonpeptide agonists and antagonists.
We have reported previously that the transmembrane domains of the cholecystokinin-B/gastrin receptor (CCK-BR) comprise a putative… (More)
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1996
1996
Autocrine loop through cholecystokinin-B/gastrin receptors involved in growth of human leukemia cells.
The cholecystokinin (CCK)-B/gastrin receptor binds two brain-gut hormones, CCK and gastrin, with high affinities. These peptides… (More)
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1994
1994
Pharmacological profile of (R)-1-[2,3-dihydro-1-(2'-methylphenacyl)-2-oxo- 5-phenyl-1H-1,4-benzodiazepin-3-yl]-3-(3-methylphenyl)urea (YM022), a new potent and selective gastrin/cholecystokinin-B…
(R)-1-[2,3-dihydro-1-(2'-methylphenacyl)-2-oxo-5-phenyl-1H-1,4- benzodiazepin-3-yl]-3-(3-methylphenyl)urea (YM022) is an… (More)
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