Xenobiotics

Known as: xenobiotic 
Chemical substances that are foreign to the biological system. They include naturally occurring compounds, drugs, environmental agents, carcinogens… (More)
National Institutes of Health

Papers overview

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Review
2017
Review
2017
Extensive research over the past half a century indicates that reactive oxygen species (ROS) play an important role in cancer… (More)
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Review
2017
Review
2017
Laccases are multicopper containing enzymes capable of performing one electron oxidation of a broad range of substrates. Using… (More)
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Review
2007
Review
2007
Irrespective of the morphological features of end-stage cell death (that may be apoptotic, necrotic, autophagic, or mitotic… (More)
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Review
2005
Review
2005
Drug metabolizing enzymes (DMEs) play central roles in the metabolism, elimination and detoxification of xenobiotics and drugs… (More)
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Review
2002
Review
2002
The nuclear pregnane X receptor (PXR; NR1I2) is an important component of the body's adaptive defense mechanism against toxic… (More)
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Highly Cited
2002
Highly Cited
2002
The nuclear pregnane X receptor (PXR) and constitutive androstane receptor (CAR) play central roles in protecting the body… (More)
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Highly Cited
2000
Highly Cited
2000
Xenobiotics induce the transcription of cytochromes P450 (CYPs) 2B and 3A through the constitutive androstane receptor (CAR… (More)
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Highly Cited
2000
Highly Cited
2000
Transcription of genes encoding cytochrome P450 3A (CYP3A) monooxygenases is induced by a variety of xenobiotics and natural… (More)
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Highly Cited
2000
Highly Cited
2000
The cytochrome P450 (CYP) gene products such as CYP3A and CYP2B are essential for the metabolism of steroid hormones and… (More)
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Review
1992
Review
1992
Metabolism of foreign chemicals (xenobiotics) by plants generally proceeds in three phases: transformation, conjugation and… (More)
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