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Xanthinol Niacinate

Known as: Xantinol Nicotinate, 3-Pyridinecarboxylic acid, compd. with 3,7-dihydro-7-(2-hydroxy-3-((2-hydroxyethyl)methylamino)propyl)-1,3-dimethyl-1H-purine-2,6-dione (1:1), Nicotinate, Xanthinol 
A vasodilator used in peripheral vascular disorders and insufficiency. It may cause gastric discomfort and hypotension.
National Institutes of Health

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13 relations

Narrower (4)

ComplaminSadaminTeonicolXavin
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Broader (2)

Vasodilator AgentsXanthinol

Papers overview

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1981
1981
The effect of food on the absorption of alpha-tocopheryl nicotinate in beagle dogs and human volunteers.
The effect of food on absorption of d,1-alpha-tocopheryl nicotinate was studied in cross-over studies with eight beagle dogs and… 
1979
1979
Nocturnal inhibition of lipolysis in man by nicotinic acid and derivatives
SummaryThe effect of nicotinic acid and several derivatives on the nocturnal level of free fatty acids was studied in 12 healthy… 
1979
1979
Xanthinol nicotinate in the management of leg ulcers associated with haemoglobinopathies.
The therapeutic role of xanthinol nicotinate, with its potent action on the peripheral circulation, in promoting healing of leg… 
1977
1977
A Multiclinic Double-Blind Trial of Pyridinolcarbamate and Inositol Niacinate in Ischemic Ulcer Due To Chronic Arterial Occlusion
A double-blind multiclinic trial compared the efficacies of pyridinolcarba mate and inositol niacinate in the patients with the… 
1977
1977
Influence of hypercapnia on the cerebrovascular activities of some drugs used in the treatment of cerebral ischemia.
The effects of twelve substances on local cerebral blood flow (LCBF) were studied in the normocapnic and hypercapnic conscious… 
1977
1977
Effect of xanthinol nicotinate treatment on platelet aggregation.
Treatment of 24 male patients with 3 g/day of xanthinol nicotinate did not change the in vitro measurements of ADP-induced… 
1976
1976
Comparative study of the effect of ethyl apovincaminate and xantinol nicotinate in cerebrovascular diseases. Immediate drug effects on the concentrations of carbohydrate metabolites and electrolytes…
Randomly selected 34 cerebrovascular patients were treated with ethyl apovincaminate (RGH-4405, Cavinton) and 109 with xanitinol… 
1974
1974
Superinfection Compatibility of R Factors in Shigella dysenteriae Type 1 from Central America and Salmonella typhi from Mexico
W. B. III. Effect of prostaglandin E1 on electrolyte transport in rabbit ileal mucosa [abstract]. J. Clin. Invest. 49:2a, 1970… 
1972
1972
Effects of nitroglycerin, dipyridamole, carbocromen, xanthinol nicotinate, and butallylonal on venous return.
1971
1971
Inhibition of nicotinate phosphoribosyl transferase by nonsteroidal anti-inflammatory drugs: a possible mechanism of action.
When incubated with 14C-nicotinic acid and phosphorylribose-1-pyrophosphate, human platelet lysate incorporates radioactivity…