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XR 11576

Known as: XR-11576, XR11576 
National Institutes of Health

Papers overview

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2009
2009
Effect of phenazine compounds XR11576 and XR5944 on DNA topoisomerases
PurposePrevious in vitro cleavage data showed that XR11576 and XR5944 stabilised topoisomerase I and topoisomerase II complexes… 
2007
2007
Mode of action of the novel phenazine anticancer agents XR11576 and XR5944
The substituted phenazines XR11576 and XR5944 were originally described as dual topoisomerase-I/II poisons. Subsequent reports… 
2004
2004
Ex vivo characterization of XR11576 (MLN576) against ovarian cancer and other solid tumors
XR11576 (MLN576) is a novel monophenazine with a mechanism of action that includes interaction with both topoisomerase (Topo) I… 
2004
2004
Mechanism of action of putative dual topoisomerase I and II poisons XR5944 and XR11576.
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